Protein: ESF2
Pre-rRNA-processing protein ESF2 (18S rRNA factor 2)

Gene: ESF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 115
UniProt ID: P53743

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001671 - ATPase activator activity
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864736

ESF1
Pre-rRNA-processing protein ESF1

6

1

Small-scale

0.736

High

753161

DBP8
ATP-dependent RNA helicase DBP8

4

3

Small-scale

0.707

High

634713

KRR1
KRR1 small subunit processome component

4

1

High-throughput

0.693

High

864748

UTP12
U3 small nucleolar RNA-associated protein 12

4

3

Small-scale

0.693

High

635619

PWP2
Periodic tryptophan protein 2

4

2

Small-scale

0.678

High

593674

DBP4
ATP-dependent RNA helicase HCA4

3

7

Small-scale

0.672

High

748672

ENP1
Essential nuclear protein 1

3

1

High-throughput

0.658

High

549452

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

1

Small-scale

0.650

High

816885

NOL10
Ribosome biogenesis protein ENP2

3

1

Small-scale

0.650

High

864733

UTP21
U3 small nucleolar RNA-associated protein 21

3

4

Small-scale

0.650

High

864724

HAS1
ATP-dependent RNA helicase HAS1

2

8

Small-scale

0.637

High

859394

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

1

High-throughput

0.628

High

774733

UTP25
U3 small nucleolar RNA-associated protein 25

2

1

High-throughput

0.614

High

792530

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

Small-scale

0.613

High

864717

NAT10
RNA cytidine acetyltransferase

2

1

High-throughput

0.601

High

864726

DHR1
Probable ATP-dependent RNA helicase DHR1

2

3

High-throughput

0.601

High

864732

UTP13
U3 small nucleolar RNA-associated protein 13

2

2

High-throughput

0.601

High

864745

BMS1
Ribosome biogenesis protein BMS1

2

2

High-throughput

0.601

High

864752

NOP56
Nucleolar protein 56

2

1

High-throughput

0.601

High

864754

NOP58
Nucleolar protein 58

2

1

High-throughput

0.601

High

772658

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

864715

ESF2
Pre-rRNA-processing protein ESF2

2

0

Small-scale

0.588

High

864720

UTP6
U3 small nucleolar RNA-associated protein 6

2

0

High-throughput

0.588

High

864753

RRP36
rRNA biogenesis protein RRP36

2

0

High-throughput

0.588

High

864757

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.588

High

366681

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.588

High

768096

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

1

Small-scale

0.584

High

811536

MPP10
U3 small nucleolar RNA-associated protein MPP10

2

1

Small-scale

0.584

High

860708

UTP22
U3 small nucleolar RNA-associated protein 22

2

1

Small-scale

0.584

High

864730

RRP5
rRNA biogenesis protein RRP5

2

1

Small-scale

0.584

High

864738

NOC4
Nucleolar complex protein 4

2

3

High-throughput

0.584

High

864741

UTP4
U3 small nucleolar RNA-associated protein 4

2

2

Small-scale

0.584

High

864729

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

550092

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.541

High

648408

NSR1
Nuclear localization sequence-binding protein

1

0

High-throughput

0.518

High

861439

NOP19
Nucleolar protein 19

1

0

High-throughput

0.518

High

864734

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.518

High

753040

RRP3
ATP-dependent rRNA helicase RRP3

1

5

High-throughput

0.515

High

864742

TSR1
Ribosome biogenesis protein TSR1

1

2

High-throughput

0.515

High

676252

XPO1
Exportin-1

1

0

High-throughput

0.513

High

410156

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.493

High

842768

OCA1
Putative tyrosine-protein phosphatase OCA1

1

0

High-throughput

0.493

High

407220

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

457052

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.479

High

481681

RL18B
Large ribosomal subunit protein eL18B

1

1

Small-scale

0.479

High

535070

RL3
Large ribosomal subunit protein uL3

1

1

Small-scale

0.479

High

630519

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

632009

RS2
Small ribosomal subunit protein uS5

1

2

Small-scale

0.479

High

707118

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

733581

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.479

High

767393

UTP7
U3 small nucleolar RNA-associated protein 7

1

2

High-throughput

0.479

High

776475

RLP7
Ribosome biogenesis protein RLP7

1

1

Small-scale

0.479

High

864718

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

864721

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

864725

UTP5
U3 small nucleolar RNA-associated protein 5

1

3

High-throughput

0.479

High

864727

UTP15
U3 small nucleolar RNA-associated protein 15

1

1

High-throughput

0.479

High

864737

RRP9
Ribosomal RNA-processing protein 9

1

1

High-throughput

0.479

High

864739

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

864746

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

864747

SAS10
Something about silencing protein 10

1

1

High-throughput

0.479

High

864755

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

864756

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.479

High

408423

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

625832

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

645572

RS7A
Small ribosomal subunit protein eS7A

1

0

Small-scale

0.458

High

664974

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

688354

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700082

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.458

High

711058

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

715959

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

756765

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

774264

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

775375

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

799837

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

861007

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

864731

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

864735

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

864743

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

864744

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

864758

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

864751

NSI1
RNA polymerase I termination factor

1

1

High-throughput

0.457

High

450132

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

492007

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

494601

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

512216

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

544178

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

680904

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

695224

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

705493

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

754596

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

769076

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

810391

JJJ2
J protein JJJ2

1

1

High-throughput

0.445

High

864716

JJJ1
J protein JJJ1

1

2

High-throughput

0.445

High

485792

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.438

High

636025

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.438

High

767341

YEQ9
Uncharacterized protein YER079W

1

0

High-throughput

0.438

High

864719

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.438

High

864728

KRE28
Spindle pole body component KRE28

1

0

High-throughput

0.438

High

864750

AHC1
Protein AHC1

1

0

High-throughput

0.438

High

560754

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

633443

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

811415

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

864740

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

864749

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

479509

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.269

Low

690958

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.269

Low

478945

RL20B
Large ribosomal subunit protein eL20B

1

0

Small-scale

0.249

Low

634358

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.249

Low

662932

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

762435

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

864722

SLD5
DNA replication complex GINS protein SLD5

1

0

High-throughput

0.238

Low

864723

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.238

Low

761044

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

772573

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024