Protein: JAM3
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]

Gene: JAM3
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9BX67

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001780 - neutrophil homeostasis
GO:0002250 - adaptive immune response
GO:0002318 - myeloid progenitor cell differentiation
GO:0002523 - leukocyte migration involved in inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

374172

RASN
GTPase NRas

2

20

High-throughput

0.754

High

375901

RASK
GTPase KRas

2

20

High-throughput

0.754

High

944232

JAM2
Junctional adhesion molecule B

1

16

Small-scale

0.724

High

1416520

JAM3
Junctional adhesion molecule C

1

14

Small-scale

0.724

High

1416523

CLC4A
C-type lectin domain family 4 member A

1

17

High-throughput

0.691

High

539491

ITAM
Integrin alpha-M

1

4

Small-scale

0.647

High

1058925

ZO1
Tight junction protein 1

1

19

Small-scale

0.647

High

1270972

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.647

High

1416522

PICK1
PRKCA-binding protein

2

5

Small-scale

0.636

High

1353259

PARD3
Partitioning defective 3 homolog

2

20

Small-scale

0.624

High

374894

RASH
GTPase HRas

1

20

High-throughput

0.618

High

424101

ITB2
Integrin beta-2

1

9

Small-scale

0.618

High

845781

MUC18
Cell surface glycoprotein MUC18

1

19

High-throughput

0.618

High

901015

RAB5C
Ras-related protein Rab-5C

1

14

High-throughput

0.618

High

901537

RAB7A
Ras-related protein Rab-7a

1

18

High-throughput

0.618

High

956467

RAB2A
Ras-related protein Rab-2A

1

18

High-throughput

0.618

High

978265

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

975213

ARF6
ADP-ribosylation factor 6

2

13

High-throughput

0.584

High

907564

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

High-throughput

0.553

High

530323

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.536

High

608346

EGLN
Endoglin

1

2

High-throughput

0.536

High

1416521

SPNS1
Protein spinster homolog 1

1

1

High-throughput

0.514

High

699069

CALX
Calnexin

1

16

High-throughput

0.489

High

894137

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

715750

MARCS
Myristoylated alanine-rich C-kinase substrate

1

9

High-throughput

0.479

High

941836

ARL4C
ADP-ribosylation factor-like protein 4C

1

20

High-throughput

0.479

High

1326509

ARL14
ADP-ribosylation factor-like protein 14

1

17

High-throughput

0.479

High

1232555

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.470

High

1005057

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1347861

RIN3
Ras and Rab interactor 3

1

4

High-throughput

0.437

High

1416524

ARL5A
ADP-ribosylation factor-like protein 5A

1

16

High-throughput

0.437

High


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Last updated: 11Aug2025