Protein: TYDP1
Tyrosyl-DNA phosphodiesterase 1 (Tyr-DNA phosphodiesterase 1) (EC 3.1.4.-)

Gene: TYDP1, TDP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P38319

Gene Ontology (top 5):
GO:0003690 - double-stranded DNA binding
GO:0003697 - single-stranded DNA binding
GO:0004527 - exonuclease activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

798029

SMT3
Ubiquitin-like protein SMT3

2

1

High-throughput

0.620

High

510439

HSP77
Import motor subunit, mitochondrial

2

1

High-throughput

0.552

High

673095

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.513

High

757870

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.513

High

452897

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.500

High

679619

CDC48
Cell division control protein 48

1

1

High-throughput

0.500

High

798023

YGI2
Uncharacterized protein YGL082W

1

0

High-throughput

0.493

High

798028

CTI6
Histone deacetylase complex subunit CTI6

1

0

High-throughput

0.493

High

408320

GAL1
Galactokinase

1

0

High-throughput

0.479

High

425124

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.479

High

484757

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

554916

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.479

High

555066

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.479

High

675958

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.479

High

798030

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

798026

CORO
Coronin-like protein

1

1

High-throughput

0.470

High

382067

H4
Histone H4

1

0

High-throughput

0.458

High

798024

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.458

High

798025

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

1

High-throughput

0.457

High

592213

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.457

High

523776

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526547

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544679

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741475

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

798021

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

798022

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

752193

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

531314

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.261

Low

798027

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

798020

PAC2
Protein PAC2

1

0

High-throughput

0.249

Low

631909

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025