Protein: GAL1
Galactokinase (EC 2.7.1.6) (Galactose kinase)

Gene: GAL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 116
UniProt ID: P04385

Gene Ontology (top 5):
GO:0000411 - positive regulation of transcription by galactose
GO:0000435 - positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0004335 - galactokinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

408260

GAL80
Galactose/lactose metabolism regulatory protein GAL80

6

1

Small-scale

0.732

High

391950

HSP82
ATP-dependent molecular chaperone HSP82

3

1

Small-scale

0.640

High

408281

HSC82
ATP-dependent molecular chaperone HSC82

2

1

Small-scale

0.571

High

408349

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.569

High

408259

GAL4
Regulatory protein GAL4

1

1

Small-scale

0.501

High

408263

CDC7
Cell division control protein 7

1

2

High-throughput

0.500

High

408265

RAD52
DNA repair and recombination protein RAD52

1

1

High-throughput

0.500

High

408278

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.500

High

408279

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.500

High

408284

GBB
Guanine nucleotide-binding protein subunit beta

1

3

High-throughput

0.500

High

408292

RV161
Reduced viability upon starvation protein 161

1

1

High-throughput

0.500

High

408301

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

1

High-throughput

0.500

High

408303

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.500

High

408304

IME2
Meiosis induction protein kinase IME2/SME1

1

2

High-throughput

0.500

High

408307

KU70
ATP-dependent DNA helicase II subunit 1

1

1

High-throughput

0.500

High

408315

HEL1
E3 ubiquitin-protein ligase HEL1

1

1

High-throughput

0.500

High

408317

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

1

High-throughput

0.500

High

408325

PEX7
Peroxisomal targeting signal 2 receptor

1

1

High-throughput

0.500

High

408326

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.500

High

408333

RPN14
26S proteasome regulatory subunit RPN14

1

1

High-throughput

0.500

High

408339

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.500

High

408340

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

High-throughput

0.500

High

408348

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.500

High

408352

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

4

High-throughput

0.500

High

408361

RBX1
RING-box protein HRT1

1

1

High-throughput

0.500

High

408362

RAD28
Radiation-sensitive protein 28

1

2

High-throughput

0.500

High

408364

YP150
Putative serine/threonine-protein kinase YPL150W

1

1

High-throughput

0.500

High

408366

RAD59
DNA repair protein RAD59

1

1

High-throughput

0.500

High

376253

YPT1
GTP-binding protein YPT1

1

0

High-throughput

0.479

High

404994

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.479

High

408261

DNLI1
DNA ligase 1

1

0

High-throughput

0.479

High

408262

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

408264

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.479

High

408266

RHO2
GTP-binding protein RHO2

1

0

High-throughput

0.479

High

408267

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.479

High

408268

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

1

0

High-throughput

0.479

High

408269

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.479

High

408270

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.479

High

408271

SPS1
Sporulation-specific protein 1

1

0

High-throughput

0.479

High

408274

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.479

High

408276

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.479

High

408277

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.479

High

408280

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.479

High

408282

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

High-throughput

0.479

High

408283

ABP1
Actin-binding protein

1

0

High-throughput

0.479

High

408285

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.479

High

408286

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.479

High

408287

RFA1
Replication factor A protein 1

1

0

High-throughput

0.479

High

408288

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.479

High

408290

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

High-throughput

0.479

High

408293

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.479

High

408296

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.479

High

408298

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.479

High

408299

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

High-throughput

0.479

High

408302

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.479

High

408306

RAD24
Checkpoint protein RAD24

1

0

High-throughput

0.479

High

408308

RAD54
DNA repair and recombination protein RAD54

1

0

High-throughput

0.479

High

408309

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.479

High

408313

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

0

High-throughput

0.479

High

408314

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.479

High

408319

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.479

High

408320

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.479

High

408322

RAD55
DNA repair protein RAD55

1

0

High-throughput

0.479

High

408324

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.479

High

408327

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.479

High

408328

NOP2
25S rRNA

1

0

High-throughput

0.479

High

408330

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

0

High-throughput

0.479

High

408334

SSK2
MAP kinase kinase kinase SSK2

1

0

High-throughput

0.479

High

408335

PAP2
Poly(A) RNA polymerase protein 2

1

0

High-throughput

0.479

High

408336

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.479

High

408337

SIW14
Inositol diphosphatase SIW14

1

0

High-throughput

0.479

High

408338

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.479

High

408341

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.479

High

408344

VPS64
Vacuolar protein sorting-associated protein 64

1

0

High-throughput

0.479

High

408355

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.479

High

408357

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.479

High

408358

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.479

High

408359

SHS1
Seventh homolog of septin 1

1

0

High-throughput

0.479

High

408360

PML1
Pre-mRNA leakage protein 1

1

0

High-throughput

0.479

High

408363

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.479

High

408367

PKH2
Serine/threonine-protein kinase PKH2

1

0

High-throughput

0.479

High

408368

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.479

High

408369

ATG5
Autophagy protein 5

1

0

High-throughput

0.479

High

408370

LAS17
Proline-rich protein LAS17

1

0

High-throughput

0.479

High

408371

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.479

High

408295

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

408311

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

408312

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

408346

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

408350

UFO1
Ubiquitin ligase complex F-box protein UFO1

1

0

Small-scale

0.458

High

408365

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

408316

CAF4
CCR4-associated factor 4

1

3

High-throughput

0.457

High

408323

TEM1
Protein TEM1

1

1

High-throughput

0.457

High

408342

WDR59
Maintenance of telomere capping protein 5

1

4

High-throughput

0.457

High

408345

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.457

High

408354

UTP13
U3 small nucleolar RNA-associated protein 13

1

1

High-throughput

0.457

High

408272

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

408273

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

408275

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

408305

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

408353

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

5

High-throughput

0.445

High

408300

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

408331

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

408347

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

408289

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.261

Low

408291

CDC10
Cell division control protein 10

1

0

High-throughput

0.261

Low

408297

RFA3
Replication factor A protein 3

1

0

High-throughput

0.261

Low

408310

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

High-throughput

0.261

Low

408318

MOH1
Protein yippee-like MOH1

1

0

High-throughput

0.261

Low

408321

AIM46
Altered inheritance of mitochondria protein 46, mitochondrial

1

0

High-throughput

0.261

Low

408329

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.261

Low

408332

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.261

Low

408343

YD131
F-box protein YDR131C

1

0

High-throughput

0.261

Low

408351

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.261

Low

408356

YD306
F-box protein YDR306C

1

0

High-throughput

0.261

Low

408294

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025