Protein: CTF4
DNA polymerase alpha-binding protein (Chromosome replication protein CHL15) (Chromosome transmission fidelity protein 4) (Protein POB1)

Gene: CTF4
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: Q01454

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000278 - mitotic cell cycle
GO:0000727 - double-strand break repair via break-induced replication
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

964866

SLD5
DNA replication complex GINS protein SLD5

20

1

Small-scale

0.990

High

772608

PSF2
DNA replication complex GINS protein PSF2

8

1

Small-scale

0.971

High

964883

PSF1
DNA replication complex GINS protein PSF1

7

2

Small-scale

0.965

High

964875

CDC45
Cell division control protein 45

8

1

Small-scale

0.957

High

964881

PSF3
DNA replication complex GINS protein PSF3

5

0

Small-scale

0.879

High

964863

CTF4
DNA polymerase alpha-binding protein

3

19

Small-scale

0.871

High

526858

DPOLA
DNA polymerase alpha catalytic subunit A

14

7

Small-scale

0.765

High

675548

MCM4
DNA replication licensing factor MCM4

17

10

Small-scale

0.763

High

622189

MCM3
DNA replication licensing factor MCM3

9

9

Small-scale

0.745

High

667882

MCM5
Minichromosome maintenance protein 5

7

9

Small-scale

0.736

High

964877

DIA2
Protein DIA2

7

0

Small-scale

0.722

High

964870

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

4

3

Small-scale

0.698

High

667620

MCM2
DNA replication licensing factor MCM2

4

6

Small-scale

0.676

High

859006

MCM6
DNA replication licensing factor MCM6

4

8

Small-scale

0.676

High

744789

MCM7
DNA replication licensing factor MCM7

3

6

Small-scale

0.646

High

744530

DPOA2
DNA polymerase alpha subunit B

3

0

Small-scale

0.619

High

622888

DPB2
DNA polymerase epsilon subunit B

3

0

Small-scale

0.614

High

492148

HSP71
Heat shock protein SSA1

2

19

High-throughput

0.601

High

756334

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

1

8

Small-scale

0.594

High

558205

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

1

High-throughput

0.584

High

607322

RFA1
Replication factor A protein 1

2

6

Small-scale

0.584

High

959988

SEN1
Helicase SEN1

2

9

Small-scale

0.584

High

366746

HSP82
ATP-dependent molecular chaperone HSP82

2

13

High-throughput

0.571

High

769203

SSB2
Ribosome-associated molecular chaperone SSB2

2

20

High-throughput

0.552

High

634895

MRC1
Mediator of replication checkpoint protein 1

2

0

Small-scale

0.547

High

494724

HSP72
Heat shock protein SSA2

1

19

High-throughput

0.536

High

512375

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.536

High

608756

CHL1
ATP-dependent DNA helicase CHL1

1

1

Small-scale

0.536

High

811004

CUL8
Cullin-8

1

20

Small-scale

0.536

High

964871

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.513

High

771346

PSA6
Proteasome subunit alpha type-6

1

3

High-throughput

0.508

High

565742

PHO85
Cyclin-dependent protein kinase PHO85

1

6

High-throughput

0.501

High

703257

PRP40
Pre-mRNA-processing protein PRP40

1

5

High-throughput

0.501

High

765360

RSP5
E3 ubiquitin-protein ligase RSP5

1

6

High-throughput

0.501

High

964878

ESA1
Histone acetyltransferase ESA1

1

8

Small-scale

0.501

High

659238

RAD14
DNA repair protein RAD14

1

0

High-throughput

0.493

High

964867

STE20
Serine/threonine-protein kinase STE20

1

9

Small-scale

0.481

High

659879

PRR1
Serine/threonine-protein kinase PRR1

1

0

High-throughput

0.480

High

457060

SWI6
Regulatory protein SWI6

1

8

High-throughput

0.479

High

521152

RAD50
DNA repair protein RAD50

1

8

High-throughput

0.479

High

593811

PRI2
DNA primase large subunit

1

1

Small-scale

0.479

High

602373

DPOE
DNA polymerase epsilon catalytic subunit A

1

7

Small-scale

0.479

High

606109

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

644770

RFA2
Replication factor A protein 2

1

7

Small-scale

0.479

High

663056

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

688378

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

692876

SPT16
FACT complex subunit SPT16

1

4

High-throughput

0.479

High

730886

CENPA
Histone H3-like centromeric protein CSE4

1

14

High-throughput

0.479

High

751283

RFC3
Replication factor C subunit 3

1

8

Small-scale

0.479

High

772263

RFC4
Replication factor C subunit 4

1

5

Small-scale

0.479

High

772432

RFC2
Replication factor C subunit 2

1

5

Small-scale

0.479

High

797927

RSC8
Chromatin structure-remodeling complex protein RSC8

1

8

High-throughput

0.479

High

809846

RSF2
Respiration factor 2

1

2

High-throughput

0.479

High

964869

POB3
FACT complex subunit POB3

1

7

High-throughput

0.479

High

488498

PRI1
DNA primase small subunit

1

0

Small-scale

0.458

High

550569

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

625835

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

631682

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

688663

MCM10
Minichromosome maintenance protein 10

1

0

Small-scale

0.458

High

697628

DRI1
Putative RNA-binding protein involved in heterochromatin assembly

1

0

High-throughput

0.458

High

744289

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.458

High

964865

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.458

High

964879

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

964880

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.458

High

605759

NPR1
Nitrogen permease reactivator protein

1

7

High-throughput

0.457

High

771582

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

High-throughput

0.457

High

798328

TOS3
Serine/threonine-protein kinase TOS3

1

3

High-throughput

0.457

High

633491

MAS5
Mitochondrial protein import protein MAS5

1

12

High-throughput

0.445

High

695316

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

696044

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

754633

SSZ1
Ribosome-associated complex subunit SSZ1

1

12

High-throughput

0.445

High

544255

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.437

High

561127

CDC23
Anaphase-promoting complex subunit CDC23

1

6

High-throughput

0.437

High

606286

VPS15
Serine/threonine-protein kinase VPS15

1

2

High-throughput

0.437

High

668091

TRXB1
Thioredoxin reductase 1

1

2

High-throughput

0.437

High

687615

DGR2
2-deoxy-glucose resistant protein 2

1

17

High-throughput

0.437

High

699805

KPR1
Ribose-phosphate pyrophosphokinase 1

1

4

High-throughput

0.437

High

701041

SMY2
Protein SMY2

1

2

High-throughput

0.437

High

743478

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

3

High-throughput

0.437

High

748819

RGD1
RHO GTPase-activating protein RGD1

1

2

High-throughput

0.437

High

750994

KPR2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.437

High

819508

BUL1
Ubiquitin ligase-binding protein BUL1

1

2

High-throughput

0.437

High

858377

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

8

High-throughput

0.437

High

541775

SEC63
Protein translocation protein SEC63

1

9

High-throughput

0.407

High

556239

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.407

High

760932

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.407

High

766160

HSP7E
Heat shock protein SSC3, mitochondrial

1

15

High-throughput

0.407

High

766537

PFD2
Prefoldin subunit 2

1

3

High-throughput

0.407

High

785166

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

865903

PFD4
Prefoldin subunit 4

1

4

High-throughput

0.407

High

964868

PFD5
Prefoldin subunit 5

1

5

High-throughput

0.407

High

964873

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

8

High-throughput

0.407

High

964882

HSP42
Heat shock protein 42

1

4

High-throughput

0.407

High

964864

TOF2
Topoisomerase 1-associated factor 2

1

0

Small-scale

0.309

High

613137

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.249

Low

710861

ZRT3
Zinc-regulated transporter 3

1

0

High-throughput

0.249

Low

711149

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.249

Low

716121

THI80
Thiamine pyrophosphokinase

1

0

High-throughput

0.249

Low

734094

OMA1
Mitochondrial metalloendopeptidase OMA1

1

0

High-throughput

0.249

Low

753327

MUP3
Low-affinity methionine permease

1

0

High-throughput

0.249

Low

767013

FIR1
Factor interacting with REF2

1

0

High-throughput

0.249

Low

859189

YIP5
Protein YIP5

1

0

High-throughput

0.249

Low

964872

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.249

Low

964874

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

964876

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

810110

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024