Protein: TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase (EC 4.1.3.44) (tRNA wybutosine-synthesizing protein 1)

Gene: TYW1
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: Q08960

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0010181 - FMN binding
GO:0031591 - wybutosine biosynthetic process
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597915

PWP1
Periodic tryptophan protein 1

2

1

High-throughput

0.802

High

751241

NCB5R
NADH-cytochrome b5 reductase 1

1

9

High-throughput

0.618

High

997027

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

6

High-throughput

0.618

High

979115

RRB1
Ribosome assembly protein RRB1

1

1

High-throughput

0.595

High

495201

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

367036

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.541

High

513056

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.536

High

769703

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.536

High

752232

KSP1
Serine/threonine-protein kinase KSP1

1

2

High-throughput

0.501

High

988727

CSR1
Phosphatidylinositol transfer protein CSR1

1

0

High-throughput

0.493

High

663572

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

771664

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.479

High

977741

GLRX3
Monothiol glutaredoxin-3

1

2

High-throughput

0.479

High

982802

RTN1
Reticulon-like protein 1

1

5

High-throughput

0.479

High

997026

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

524473

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

615311

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

625851

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

679942

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

High-throughput

0.458

High

689124

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

759216

GAA1
GPI transamidase component GAA1

1

0

High-throughput

0.458

High

865585

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

976996

LIP1
Ceramide synthase subunit LIP1

1

0

High-throughput

0.458

High

995819

SGO1
Shugoshin

1

0

High-throughput

0.458

High

478591

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.445

High

492715

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

629070

SCJ1
DnaJ-related protein SCJ1

1

5

High-throughput

0.445

High

633660

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

695719

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

988603

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.445

High

745923

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

368477

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

628556

SIS1
Protein SIS1

1

6

High-throughput

0.407

High

858579

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.279

Low

859814

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.279

Low

745511

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.249

Low

775462

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.249

Low

866632

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.249

Low

757478

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024