Protein: P5CR
Pyrroline-5-carboxylate reductase (P5C reductase) (P5CR) (EC 1.5.1.2) (PCA reductase)

Gene: P5CR, proC
Organism: Escherichia coli K-12
Interactions: 31
UniProt ID: P0A9L8

Gene Ontology (top 5):
GO:0004735 - pyrroline-5-carboxylate reductase activity
GO:0005829 - cytosol
GO:0042802 - identical protein binding
GO:0055129 - L-proline biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

496880

PROQ
RNA chaperone ProQ

1

0

High-throughput

0.518

High

495192

PSRP
Phosphoenolpyruvate synthase regulatory protein

1

0

High-throughput

0.513

High

496879

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

480577

PFLB
Formate acetyltransferase 1

1

1

High-throughput

0.479

High

490584

ENO
Enolase

1

2

High-throughput

0.479

High

492425

RL11
Large ribosomal subunit protein uL11

1

2

High-throughput

0.479

High

493218

RS10
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

494368

RS8
Small ribosomal subunit protein uS8

1

1

High-throughput

0.479

High

495163

YEBC
Probable transcriptional regulatory protein YebC

1

2

High-throughput

0.479

High

496501

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

1

1

High-throughput

0.479

High

496873

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.479

High

496874

DBHB
DNA-binding protein HU-beta

1

1

High-throughput

0.479

High

496882

MDH
Malate dehydrogenase

1

2

High-throughput

0.479

High

496885

GRCA
Autonomous glycyl radical cofactor

1

1

High-throughput

0.479

High

359549

FRDA
Fumarate reductase flavoprotein subunit

1

0

High-throughput

0.458

High

492092

PPK1
Polyphosphate kinase

1

0

High-throughput

0.458

High

492374

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

494916

TIG
Trigger factor

1

0

High-throughput

0.458

High

496199

FABB
3-oxoacyl-[acyl-carrier-protein] synthase 1

1

0

High-throughput

0.458

High

496334

DPO3B
Beta sliding clamp

1

0

High-throughput

0.458

High

496871

DKSA
RNA polymerase-binding transcription factor DksA

1

0

High-throughput

0.458

High

496875

AHPC
Alkyl hydroperoxide reductase C

1

0

High-throughput

0.458

High

496876

RRAB
Regulator of ribonuclease activity B

1

0

High-throughput

0.458

High

496881

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

496883

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

496886

DCEB
Glutamate decarboxylase beta

1

0

High-throughput

0.458

High

496884

CUTC
PF03932 family protein CutC

1

0

High-throughput

0.279

Low

493469

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.249

Low

496872

DPS
DNA protection during starvation protein

1

0

High-throughput

0.249

Low

496877

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.249

Low

496878

RS1
Small ribosomal subunit protein bS1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025