Protein: PP11
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)

Gene: PP11, SIT4
Organism: Saccharomyces cerevisiae S288C
Interactions: 129
UniProt ID: P20604

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000159 - protein phosphatase type 2A complex
GO:0002098 - tRNA wobble uridine modification
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594364

TAP42
Type 2A phosphatase-associated protein 42

10

20

Small-scale

0.975

High

594330

PTPA1
Serine/threonine-protein phosphatase 2A activator 1

6

11

Small-scale

0.941

High

594336

SA155
SIT4-associating protein SAP155

11

7

Small-scale

0.759

High

594333

SA185
SIT4-associating protein SAP185

10

7

Small-scale

0.756

High

594376

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

2

11

Small-scale

0.754

High

594313

SA190
SIT4-associating protein SAP190

8

7

Small-scale

0.753

High

594356

ACAC
Acetyl-CoA carboxylase

4

5

High-throughput

0.699

High

594321

TCPB
T-complex protein 1 subunit beta

4

20

High-throughput

0.697

High

594292

PP11
Serine/threonine-protein phosphatase PP1-1

1

12

High-throughput

0.665

High

594300

HRR25
Casein kinase I homolog HRR25

2

12

Small-scale

0.639

High

594347

MDS3
Negative regulator of sporulation MDS3

3

0

Small-scale

0.634

High

510236

SSB1
Ribosome-associated molecular chaperone SSB1

3

15

High-throughput

0.633

High

594350

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

2

1

High-throughput

0.628

High

594310

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

2

20

High-throughput

0.621

High

594326

BEM2
GTPase-activating protein BEM2/IPL2

2

6

High-throughput

0.621

High

594371

HRK1
Serine/threonine-protein kinase HRK1

2

12

High-throughput

0.621

High

594306

ARP2
Actin-related protein 2

1

8

High-throughput

0.618

High

594334

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.611

High

594324

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.609

High

389685

CDC25
Cell division control protein 25

2

0

High-throughput

0.595

High

594338

TCPQ
T-complex protein 1 subunit theta

2

20

High-throughput

0.594

High

519892

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.593

High

594368

ELP1
Elongator complex protein 1

2

0

Small-scale

0.588

High

555805

VATB
V-type proton ATPase subunit B

2

2

High-throughput

0.584

High

594346

DXO
Decapping nuclease RAI1

2

0

High-throughput

0.563

High

594353

SWT21
Protein SWT21

2

0

High-throughput

0.563

High

594369

DTD
D-aminoacyl-tRNA deacylase

2

0

High-throughput

0.563

High

594322

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.558

High

594323

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.558

High

594335

ATG18
Autophagy-related protein 18

2

3

Small-scale

0.558

High

477890

HSP77
Import motor subunit, mitochondrial

2

20

High-throughput

0.552

High

490316

HSP71
Heat shock protein SSA1

2

14

High-throughput

0.552

High

493179

HSP72
Heat shock protein SSA2

2

14

High-throughput

0.552

High

594307

HSP7F
Heat shock protein homolog SSE1

2

19

High-throughput

0.552

High

594327

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.552

High

562316

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.536

High

594295

CDC15
Cell division control protein 15

1

20

High-throughput

0.536

High

594303

XPO1
Exportin-1

1

5

High-throughput

0.536

High

594308

TOR2
Serine/threonine-protein kinase TOR2

1

11

Small-scale

0.536

High

594339

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.536

High

594340

ADK
Adenosine kinase

1

1

High-throughput

0.536

High

594341

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

7

High-throughput

0.536

High

594342

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

1

High-throughput

0.536

High

594348

SGF73
SAGA-associated factor 73

1

1

High-throughput

0.536

High

594351

PRS10
26S proteasome subunit RPT4

1

12

High-throughput

0.536

High

594355

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

9

High-throughput

0.536

High

594362

CTK1
CTD kinase subunit alpha

1

12

High-throughput

0.536

High

594378

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.536

High

594316

SDS24
Protein SDS24

1

5

High-throughput

0.515

High

594317

RCK2
Serine/threonine-protein kinase RCK2

1

15

High-throughput

0.515

High

456678

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

0

High-throughput

0.513

High

587287

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.513

High

594311

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.513

High

594358

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.513

High

594359

RMT2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.513

High

594363

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.513

High

594365

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.513

High

477119

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

13

High-throughput

0.501

High

342659

ENO1
Enolase 1

1

1

High-throughput

0.500

High

360734

TBB
Tubulin beta chain

1

6

High-throughput

0.500

High

372801

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

3

High-throughput

0.500

High

389220

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

410904

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

439544

GAL7
Galactose-1-phosphate uridylyltransferase

1

1

High-throughput

0.500

High

449904

HSP73
Heat shock protein SSA3

1

14

High-throughput

0.500

High

454550

TBA3
Tubulin alpha-3 chain

1

8

High-throughput

0.500

High

505144

PYC1
Pyruvate carboxylase 1

1

5

High-throughput

0.500

High

554548

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

560557

BIP
Endoplasmic reticulum chaperone BiP

1

15

High-throughput

0.500

High

562179

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

4

High-throughput

0.500

High

594293

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.500

High

594294

CDC48
Cell division control protein 48

1

7

High-throughput

0.500

High

594301

BMH1
Protein BMH1

1

4

High-throughput

0.500

High

594309

PRS6B
26S proteasome regulatory subunit 6B homolog

1

4

High-throughput

0.500

High

594325

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.500

High

594361

RUVB1
RuvB-like protein 1

1

8

High-throughput

0.500

High

594374

HSP42
Heat shock protein 42

1

2

High-throughput

0.500

High

594375

HRT3
F-box protein HRT3

1

0

High-throughput

0.493

High

594319

SFB3
SED5-binding protein 3

1

2

Small-scale

0.489

High

594320

SEC31
Protein transport protein SEC31

1

12

Small-scale

0.489

High

594302

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

1

High-throughput

0.489

High

594328

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

3

High-throughput

0.489

High

594377

GLT1
Glutamate synthase [NADH]

1

3

High-throughput

0.489

High

381421

GAL1
Galactokinase

1

0

High-throughput

0.479

High

410755

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.479

High

424992

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.479

High

498435

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

537353

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

594297

URA7
CTP synthase 1

1

0

High-throughput

0.479

High

375273

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

Small-scale

0.479

High

419801

SNF1
Carbon catabolite-derepressing protein kinase

1

6

Small-scale

0.479

High

593815

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

4

Small-scale

0.479

High

594299

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

594305

KNS1
Dual specificity protein kinase KNS1

1

11

Small-scale

0.479

High

594345

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

3

High-throughput

0.479

High

594349

SDS23
Protein SDS23

1

5

High-throughput

0.479

High

594352

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

594357

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

594367

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

594373

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

594372

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

546682

SEC23
Protein transport protein SEC23

1

1

Small-scale

0.457

High

594331

SEC24
Protein transport protein SEC24

1

2

Small-scale

0.457

High

594370

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

4

Small-scale

0.457

High

378282

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.457

High

427173

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.457

High

566522

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.457

High

587923

HSP60
Heat shock protein 60, mitochondrial

1

14

High-throughput

0.457

High

594298

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

2

High-throughput

0.457

High

594332

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

594337

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.457

High

594354

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.457

High

367734

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

594366

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

20

High-throughput

0.445

High

341917

ATPB
ATP synthase subunit beta, mitochondrial

1

2

Small-scale

0.437

High

594329

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.437

High

594296

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

15

Small-scale

0.417

High

382948

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.407

High

594343

HLJ1
Protein HLJ1

1

3

High-throughput

0.407

High

594314

RM03
Large ribosomal subunit protein mL44

3

0

High-throughput

0.345

High

594312

MIA40
Mitochondrial intermembrane space import and assembly protein 40

3

0

High-throughput

0.335

High

594344

AVT4
Vacuolar amino acid transporter 4

2

0

High-throughput

0.307

High

549645

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.279

Low

594304

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.279

Low

594315

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

594318

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.279

Low

594360

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

0

Small-scale

0.261

Low

381683

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024