Protein: PFS2
Polyadenylation factor subunit 2

Gene: PFS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: P42841

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006397 - mRNA processing
GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
GO:0031124 - mRNA 3'-end processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

843181

CFT1
Protein CFT1

8

20

Small-scale

0.968

High

843178

YTH1
mRNA 3'-end-processing protein YTH1

6

5

Small-scale

0.943

High

781144

SWD2
COMPASS component SWD2

5

19

Small-scale

0.919

High

671420

RNA14
mRNA 3'-end-processing protein RNA14

4

18

Small-scale

0.911

High

632692

DBP4
ATP-dependent RNA helicase HCA4

2

18

High-throughput

0.802

High

843177

PTA1
Pre-tRNA-processing protein PTA1

14

1

Small-scale

0.760

High

843169

FIP1
Pre-mRNA polyadenylation factor FIP1

7

2

Small-scale

0.750

High

843179

YSH1
Endoribonuclease YSH1

7

11

Small-scale

0.750

High

843184

CFT2
Cleavage factor two protein 2

7

11

Small-scale

0.749

High

712926

PAP
Poly(A) polymerase

8

3

Small-scale

0.748

High

776478

MPE1
Protein MPE1

7

2

Small-scale

0.745

High

837276

REF2
RNA end formation protein 2

8

0

Small-scale

0.717

High

743239

PP12
Serine/threonine-protein phosphatase PP1-2

5

12

Small-scale

0.712

High

814981

PTI1
Protein PTI1

6

0

Small-scale

0.699

High

843176

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

5

0

Small-scale

0.689

High

554010

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.618

High

810708

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

811106

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.618

High

823611

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.618

High

813664

SWD1
COMPASS component SWD1

1

18

Small-scale

0.618

High

676089

MAS5
Mitochondrial protein import protein MAS5

2

12

High-throughput

0.584

High

626781

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.578

High

810965

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.578

High

843168

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.578

High

843170

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.578

High

545261

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.552

High

722027

XPO1
Exportin-1

1

15

High-throughput

0.536

High

843173

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.517

High

843185

YRA1
RNA annealing protein YRA1

1

15

High-throughput

0.515

High

712598

RL8B
Large ribosomal subunit protein eL8B

1

10

High-throughput

0.514

High

843172

HGH1
Protein HGH1

1

0

High-throughput

0.513

High

843182

PSK2
Serine/threonine-protein kinase PSK2

1

13

High-throughput

0.501

High

843183

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

2

Small-scale

0.501

High

590657

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

809343

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

625021

PRP6
Pre-mRNA-splicing factor 6

1

20

High-throughput

0.479

High

707395

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

843171

JHD2
Histone demethylase JHD2

1

10

Small-scale

0.479

High

672109

PUF4
Pumilio homology domain family member 4

1

4

High-throughput

0.470

High

843180

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

416449

HXKA
Hexokinase-1

1

1

High-throughput

0.457

High

599040

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

5

High-throughput

0.457

High

531783

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.445

High

741787

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

811332

CAJ1
Protein CAJ1

1

15

High-throughput

0.445

High

819032

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

843174

RL4B
Large ribosomal subunit protein uL4B

1

6

High-throughput

0.445

High

680596

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

6

High-throughput

0.437

High

843175

YPT32
GTP-binding protein YPT32/YPT11

1

5

High-throughput

0.437

High

510581

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.407

High

739396

ZUO1
Zuotin

1

16

High-throughput

0.407

High

752390

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

816261

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.407

High

627763

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

High-throughput

0.269

Low

744793

LAA2
Clathrin adapter accessory protein LAA2

1

0

High-throughput

0.269

Low

803738

YHI9
Uncharacterized isomerase YHI9

1

0

High-throughput

0.269

Low

814105

GIP4
GLC7-interacting protein 4

1

0

High-throughput

0.269

Low

797753

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025