Protein: PCF11
Protein PCF11 (protein 1 of CF I)

Gene: PCF11
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: P39081

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

811246

CLP1
mRNA cleavage and polyadenylation factor CLP1

19

4

Small-scale

0.989

High

402007

RPB1
DNA-directed RNA polymerase II subunit RPB1

7

5

Small-scale

0.953

High

671448

RNA15
mRNA 3'-end-processing protein RNA15

20

3

Small-scale

0.766

High

671416

RNA14
mRNA 3'-end-processing protein RNA14

14

4

Small-scale

0.763

High

811237

YSH1
Endoribonuclease YSH1

5

3

Small-scale

0.712

High

811249

CFT2
Cleavage factor two protein 2

5

3

Small-scale

0.712

High

811252

YRA1
RNA annealing protein YRA1

3

3

Small-scale

0.674

High

811227

PTA1
Pre-tRNA-processing protein PTA1

3

2

Small-scale

0.655

High

712921

PAP
Poly(A) polymerase

3

0

Small-scale

0.634

High

470528

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

3

Small-scale

0.629

High

811204

PCF11
Protein PCF11

1

4

Small-scale

0.621

High

707116

TF2B
Transcription initiation factor IIB

3

0

Small-scale

0.613

High

811216

LSM8
LSM2-LSM8 complex subunit LSM8

2

1

High-throughput

0.603

High

776467

MPE1
Protein MPE1

2

0

High-throughput

0.595

High

585939

CSK21
Casein kinase II subunit alpha

2

1

High-throughput

0.588

High

811241

CFT1
Protein CFT1

2

2

Small-scale

0.584

High

403514

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

1

Small-scale

0.571

High

811229

ADA2
SAGA complex subunit ADA2

2

0

High-throughput

0.565

High

811239

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.565

High

394569

EF1A
Elongation factor 1-alpha

2

0

High-throughput

0.559

High

802079

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.536

High

811219

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.536

High

689215

RL16B
Large ribosomal subunit protein uL13B

1

0

High-throughput

0.513

High

626741

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.500

High

811238

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

811214

SERB
Phosphoserine phosphatase

1

0

Small-scale

0.480

High

709756

BMH1
Protein BMH1

1

0

High-throughput

0.479

High

594372

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

680584

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

1

High-throughput

0.479

High

811223

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

1

Small-scale

0.479

High

811242

SUB2
ATP-dependent RNA helicase SUB2

1

2

Small-scale

0.479

High

513865

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

734985

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

757487

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.458

High

811217

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

811251

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

811253

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

448171

HAP2
Transcriptional activator HAP2

1

2

High-throughput

0.457

High

752003

PACC
pH-response transcription factor pacC/RIM101

1

1

High-throughput

0.457

High

811215

FIP1
Pre-mRNA polyadenylation factor FIP1

1

1

High-throughput

0.457

High

811240

MLC2
Myosin light chain 2

1

1

High-throughput

0.457

High

811257

NOP56
Nucleolar protein 56

1

2

High-throughput

0.457

High

544897

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

811212

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

811218

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

452775

IPMK
Inositol polyphosphate multikinase

1

0

High-throughput

0.438

High

533520

AK
Aspartokinase

1

0

High-throughput

0.438

High

670268

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.438

High

678677

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.438

High

687053

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.438

High

746347

RAD54
DNA repair and recombination protein RAD54

1

0

High-throughput

0.438

High

753083

NIP80
Protein NIP100

1

0

High-throughput

0.438

High

754431

NPL4
Nuclear protein localization protein 4

1

0

High-throughput

0.438

High

779678

YPT53
GTP-binding protein YPT53

1

0

High-throughput

0.438

High

811206

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.438

High

811207

SAP1
Protein SAP1

1

0

High-throughput

0.438

High

811208

ARB1
ABC transporter ATP-binding protein ARB1

1

0

High-throughput

0.438

High

811211

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.438

High

811213

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.438

High

811220

ART5
Arrestin-related trafficking adapter 5

1

0

High-throughput

0.438

High

811222

ZPR1
Zinc finger chaperone ZPR1

1

0

High-throughput

0.438

High

811225

CNM67
Chaotic nuclear migration protein 67

1

0

High-throughput

0.438

High

811228

MEH1
Protein MEH1

1

0

High-throughput

0.438

High

811231

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.438

High

811235

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

0

High-throughput

0.438

High

811243

SHS1
Seventh homolog of septin 1

1

0

High-throughput

0.438

High

811244

NBA1
Protein NBA1

1

0

High-throughput

0.438

High

811247

SNX3
Sorting nexin-3

1

0

High-throughput

0.438

High

811248

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.438

High

811250

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.438

High

811254

TIP41
Type 2A phosphatase activator TIP41

1

0

High-throughput

0.438

High

811255

WTM2
Transcriptional modulator WTM2

1

0

High-throughput

0.438

High

811258

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.438

High

149768

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.426

High

433207

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.426

High

510494

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

526712

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

712571

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.426

High

811226

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.426

High

597611

CDC23
Anaphase-promoting complex subunit CDC23

1

1

High-throughput

0.417

High

811210

SHO1
High osmolarity signaling protein SHO1

2

0

High-throughput

0.314

High

811259

ATG11
Autophagy-related protein 11

2

0

High-throughput

0.307

High

541158

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

811230

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low

150344

YP076
Putative uncharacterized protein YPR076W

1

0

High-throughput

0.238

Low

744260

ISC10
Meiosis-specific protein ISC10

1

0

High-throughput

0.238

Low

780522

YKO7
Putative uncharacterized protein YKL147C

1

0

High-throughput

0.238

Low

796802

EXO84
Exocyst complex component EXO84

1

0

High-throughput

0.238

Low

802987

YHE9
Uncharacterized protein YHL049C

1

0

High-throughput

0.238

Low

811205

GEM1
Mitochondrial Rho GTPase 1

1

0

High-throughput

0.238

Low

811209

NU157
Nucleoporin NUP157

1

0

High-throughput

0.238

Low

811221

PEX8
Peroxisomal biogenesis factor 8

1

0

High-throughput

0.238

Low

811224

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.238

Low

811232

RAV2
Regulator of V-ATPase in vacuolar membrane protein 2

1

0

High-throughput

0.238

Low

811233

GMC1
Putative multicopper oxidase GMC1

1

0

High-throughput

0.238

Low

811234

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.238

Low

811236

PIG1
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

1

0

High-throughput

0.238

Low

811245

THI72
Thiamine transporter THI72

1

0

High-throughput

0.238

Low

811256

LPX1
Peroxisomal membrane protein LPX1

1

0

High-throughput

0.238

Low

811260

YL149
Uncharacterized protein YLR149C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025