Protein: SAC3
Nuclear mRNA export protein SAC3 (Leucine permease transcriptional regulator)

Gene: SAC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: P46674

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006283 - transcription-coupled nucleotide-excision repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858373

SUS1
SAGA complex subunit SUS1

14

2

Small-scale

0.982

High

858365

THP1
Nuclear mRNA export protein THP1

15

7

Small-scale

0.981

High

445348

CDC31
Cell division control protein 31

9

6

Small-scale

0.970

High

314884

SEM1
26S proteasome complex subunit SEM1

6

1

Small-scale

0.932

High

858374

MEX67
mRNA export factor MEX67

3

2

Small-scale

0.667

High

824737

MLP2
Protein MLP2

3

3

High-throughput

0.640

High

858349

MLP1
Protein MLP1

3

2

Small-scale

0.640

High

858355

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.631

High

758037

MTR2
mRNA transport regulator MTR2

3

0

Small-scale

0.627

High

858364

SUB2
ATP-dependent RNA helicase SUB2

2

3

Small-scale

0.601

High

634251

NUP1
Nucleoporin NUP1

3

2

Small-scale

0.599

High

858351

NU116
Nucleoporin NUP116/NSP116

2

6

Small-scale

0.584

High

632807

DBP5
ATP-dependent RNA helicase DBP5

2

0

Small-scale

0.559

High

738869

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

0

Small-scale

0.559

High

813635

NUP60
Nucleoporin NUP60

2

0

Small-scale

0.559

High

858348

ADA2
SAGA complex subunit ADA2

2

0

Small-scale

0.559

High

577314

NSP1
Nucleoporin NSP1

2

5

Small-scale

0.549

High

793942

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

3

High-throughput

0.536

High

858357

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.513

High

825407

PRK1
Actin-regulating kinase PRK1

1

1

Small-scale

0.501

High

858339

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.493

High

858361

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

735638

SMY1
Kinesin-related protein SMY1

1

1

High-throughput

0.481

High

755257

NUF2
Kinetochore protein NUF2

1

1

High-throughput

0.481

High

777073

BDF1
Bromodomain-containing factor 1

1

4

High-throughput

0.481

High

858353

SGF11
SAGA complex subunit SGF11

1

0

Small-scale

0.480

High

736669

ASF1
Histone chaperone ASF1

1

1

Small-scale

0.479

High

757502

NCBP1
Nuclear cap-binding protein complex subunit 1

1

1

High-throughput

0.479

High

762980

SPT7
SAGA complex subunit SPT7

1

3

Small-scale

0.479

High

792116

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

800660

KPR2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.479

High

817799

NU157
Nucleoporin NUP157

1

2

High-throughput

0.479

High

817838

GLE2
mRNA export factor GLE2

1

3

High-throughput

0.479

High

825155

NU159
Nucleoporin NUP159

1

2

High-throughput

0.479

High

858333

SAC3
Nuclear mRNA export protein SAC3

1

2

High-throughput

0.479

High

858347

NUP49
Nucleoporin NUP49/NSP49

1

4

High-throughput

0.479

High

858350

NU100
Nucleoporin NUP100/NSP100

1

6

High-throughput

0.479

High

858360

YSH1
Endoribonuclease YSH1

1

1

High-throughput

0.479

High

858370

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.479

High

809119

AKR1
Palmitoyltransferase AKR1

1

1

High-throughput

0.470

High

460350

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.460

High

736997

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

779772

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.460

High

782581

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

796326

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

809197

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

836575

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

858336

BRO1
Vacuolar-sorting protein BRO1

1

0

High-throughput

0.460

High

858340

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

455131

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

579625

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

605906

HPR1
THO complex subunit HPR1

1

0

High-throughput

0.458

High

689531

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

776525

NU120
Nucleoporin NUP120

1

0

High-throughput

0.458

High

778396

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

782532

NU133
Nucleoporin NUP133

1

0

High-throughput

0.458

High

802245

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

805191

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

0

Small-scale

0.458

High

805746

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

812862

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

High-throughput

0.458

High

817428

THO1
Protein THO1

1

0

High-throughput

0.458

High

823478

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.458

High

858306

NUP85
Nucleoporin NUP85

1

0

High-throughput

0.458

High

858334

NU192
Nucleoporin NUP192

1

0

High-throughput

0.458

High

858337

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

858342

NUP84
Nucleoporin NUP84

1

0

High-throughput

0.458

High

858344

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

Small-scale

0.458

High

858345

THO2
THO complex subunit 2

1

0

High-throughput

0.458

High

858346

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

858352

IMA1
Importin subunit alpha

1

0

High-throughput

0.458

High

858359

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

858362

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

858366

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

Small-scale

0.458

High

858367

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

0

High-throughput

0.458

High

858369

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

858371

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.458

High

524350

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

545337

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

741838

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

819096

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

504282

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

795067

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

858338

NUP57
Nucleoporin NUP57

1

4

High-throughput

0.437

High

858343

SEH1
Nucleoporin SEH1

1

4

High-throughput

0.437

High

858354

NUP53
Nucleoporin NUP53

1

1

High-throughput

0.437

High

858356

SEC13
Protein transport protein SEC13

1

4

High-throughput

0.437

High

858358

NUP59
Nucleoporin ASM4

1

1

High-throughput

0.437

High

858368

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

676109

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

804253

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

816271

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

858335

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

858363

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.407

High

562965

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.269

Low

818118

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.265

Low

94569

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

849696

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

410204

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

753445

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

756635

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.249

Low

858341

NU188
Nucleoporin NUP188

1

0

High-throughput

0.249

Low

858372

POM34
Nucleoporin POM34

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025