Protein: DNAA
Chromosomal replication initiator protein DnaA (EC 3.6.4.-)

Gene: DNAA
Organism: Escherichia coli K-12
Interactions: 46
UniProt ID: P03004

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

395076

DNAB
Replicative DNA helicase DnaB

4

1

Small-scale

0.893

High

395056

DNAA
Chromosomal replication initiator protein DnaA

2

5

Small-scale

0.755

High

395095

HDA
DnaA regulatory inactivator Hda

1

5

Small-scale

0.724

High

395089

RL2
Large ribosomal subunit protein uL2

3

0

Small-scale

0.629

High

395077

DBHA
DNA-binding protein HU-alpha

3

0

Small-scale

0.627

High

395087

NADE
NH(3)-dependent NAD(+) synthetase

2

0

High-throughput

0.613

High

395084

EFTU1
Elongation factor Tu 1

2

1

High-throughput

0.611

High

382611

RS7
Small ribosomal subunit protein uS7

2

0

High-throughput

0.602

High

395094

DIAA
DnaA initiator-associating protein DiaA

2

0

Small-scale

0.592

High

395071

RS9
Small ribosomal subunit protein uS9

2

0

High-throughput

0.585

High

395066

RS20
Small ribosomal subunit protein bS20

2

0

High-throughput

0.563

High

395068

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.563

High

395080

RL14
Large ribosomal subunit protein uL14

2

0

High-throughput

0.563

High

395091

RL24
Large ribosomal subunit protein uL24

2

0

High-throughput

0.563

High

395092

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.563

High

395058

CREC
Sensor protein CreC

1

0

High-throughput

0.537

High

395059

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.537

High

395075

DPS
DNA protection during starvation protein

1

0

Small-scale

0.527

High

395057

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

1

0

High-throughput

0.513

High

395060

CH60
Chaperonin GroEL

1

0

High-throughput

0.513

High

395061

RECF
DNA replication and repair protein RecF

1

0

High-throughput

0.513

High

395070

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

395072

LON
Lon protease

1

0

High-throughput

0.513

High

395073

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

395079

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.513

High

395088

SYD
Aspartate--tRNA ligase

1

0

High-throughput

0.513

High

395090

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

395085

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.500

High

395067

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.489

High

395062

RL7
Large ribosomal subunit protein bL12

1

1

High-throughput

0.484

High

395064

RS10
Small ribosomal subunit protein uS10

1

2

High-throughput

0.484

High

395063

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.464

High

395065

RS13
Small ribosomal subunit protein uS13

1

0

High-throughput

0.464

High

395093

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

395069

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.458

High

395074

ADHE
Bifunctional aldehyde-alcohol dehydrogenase AdhE

1

0

Small-scale

0.426

High

395078

OXYR
DNA-binding transcriptional dual regulator OxyR

1

0

Small-scale

0.426

High

383980

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.318

High

395083

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.307

High

395096

YNHG
Probable L,D-transpeptidase YnhG

1

0

High-throughput

0.292

High

395097

YFDR
Uncharacterized protein YfdR

1

0

High-throughput

0.282

High

395086

DGTP
Deoxyguanosinetriphosphate triphosphohydrolase

1

0

High-throughput

0.279

Low

395098

YFDS
Uncharacterized protein YfdS

1

0

High-throughput

0.279

Low

395081

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.253

Low

395082

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025