Protein: IPL1
Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora kinase) (Increase-in-ploidy protein 1)

Gene: IPL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: P38991

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

747734

SLI15
Inner centromere protein-related protein SLI15

14

0

Small-scale

0.936

High

339634

CDK1
Cyclin-dependent kinase 1

2

7

Small-scale

0.812

High

758779

IPL1
Spindle assembly checkpoint kinase

2

14

Small-scale

0.768

High

758801

DAM1
DASH complex subunit DAM1

7

1

Small-scale

0.749

High

758784

BIM1
Protein BIM1

6

8

Small-scale

0.729

High

751115

RCK2
Serine/threonine-protein kinase RCK2

1

17

High-throughput

0.724

High

758825

ARP8
Actin-like protein ARP8

1

8

High-throughput

0.724

High

758798

BIR1
Protein BIR1

6

0

Small-scale

0.703

High

758815

RRP5
rRNA biogenesis protein RRP5

2

4

High-throughput

0.696

High

758807

H3
Histone H3

3

20

Small-scale

0.670

High

758787

NDC80
Kinetochore protein NDC80

3

20

Small-scale

0.667

High

758824

YRA1
RNA annealing protein YRA1

1

8

High-throughput

0.665

High

691903

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

4

0

Small-scale

0.662

High

514985

RNA1
Ran GTPase-activating protein 1

1

2

High-throughput

0.647

High

624687

CG22
G2/mitotic-specific cyclin-2

1

3

Small-scale

0.647

High

628051

SIS1
Protein SIS1

1

11

High-throughput

0.647

High

758823

YP150
Putative serine/threonine-protein kinase YPL150W

1

17

High-throughput

0.647

High

688524

KNS1
Dual specificity protein kinase KNS1

1

14

High-throughput

0.621

High

758808

CDC14
Tyrosine-protein phosphatase CDC14

1

8

Small-scale

0.618

High

687937

IMB3
Importin subunit beta-3

2

3

Small-scale

0.611

High

758828

NBL1
N-terminal-borealin-like protein

2

0

Small-scale

0.609

High

716092

CENPC
Inner kinetochore subunit MIF2

2

1

Small-scale

0.602

High

757268

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

11

High-throughput

0.579

High

728359

ASK1
DASH complex subunit ASK1

2

0

Small-scale

0.577

High

733401

SPC34
DASH complex subunit SPC34

2

0

Small-scale

0.577

High

758790

DSN1
Kinetochore-associated protein DSN1

2

0

Small-scale

0.569

High

757384

IF1A
Eukaryotic translation initiation factor 1A

1

1

High-throughput

0.561

High

704472

YKJ1
CRAL-TRIO domain-containing protein YKL091C

1

0

High-throughput

0.537

High

758782

RV167
Reduced viability upon starvation protein 167

1

5

High-throughput

0.515

High

758818

IMB1
Importin subunit beta-1

1

3

High-throughput

0.515

High

368061

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.501

High

389092

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.501

High

404585

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.501

High

410379

SC160
Protein SCP160

1

8

High-throughput

0.501

High

419615

RAD52
DNA repair and recombination protein RAD52

1

1

Small-scale

0.501

High

549051

TRM1
tRNA

1

3

High-throughput

0.501

High

585868

RDS2
Regulator of drug sensitivity 2

1

1

High-throughput

0.501

High

627617

NAP1
Nucleosome assembly protein

1

5

High-throughput

0.501

High

678202

PUS3
tRNA pseudouridine(38/39) synthase

1

1

High-throughput

0.501

High

689722

MDHP
Malate dehydrogenase, peroxisomal

1

2

High-throughput

0.501

High

699682

DRS1
ATP-dependent RNA helicase DRS1

1

15

High-throughput

0.501

High

704206

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

8

High-throughput

0.501

High

710488

YBF5
Deoxyribonuclease Tat-D

1

1

High-throughput

0.501

High

730798

CENPA
Histone H3-like centromeric protein CSE4

1

20

Small-scale

0.501

High

732633

YKC3
Uncharacterized protein YKL023W

1

1

High-throughput

0.501

High

748805

RGD1
RHO GTPase-activating protein RGD1

1

5

Small-scale

0.501

High

753526

OTU2
OTU domain-containing protein 2

1

9

High-throughput

0.501

High

755359

YNG2
Chromatin modification-related protein YNG2

1

2

High-throughput

0.501

High

758059

BFR1
Nuclear segregation protein BFR1

1

1

High-throughput

0.501

High

758780

STM1
Suppressor protein STM1

1

1

High-throughput

0.501

High

758783

RSP5
E3 ubiquitin-protein ligase RSP5

1

11

High-throughput

0.501

High

758786

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

15

High-throughput

0.501

High

758789

DOT5
Peroxiredoxin DOT5

1

3

High-throughput

0.501

High

758791

SYA
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.501

High

758793

MVP1
Sorting nexin MVP1

1

7

High-throughput

0.501

High

758795

ARC1
tRNA-aminoacylation cofactor ARC1

1

2

High-throughput

0.501

High

758796

MAD3
Spindle assembly checkpoint component MAD3

1

2

Small-scale

0.501

High

758802

YG3A
Uncharacterized protein YGR130C

1

20

High-throughput

0.501

High

758805

VPS75
Vacuolar protein sorting-associated protein 75

1

4

High-throughput

0.501

High

758811

HAS1
ATP-dependent RNA helicase HAS1

1

13

High-throughput

0.501

High

758812

GLRX3
Monothiol glutaredoxin-3

1

4

High-throughput

0.501

High

758817

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.501

High

758822

CMS1
Protein CMS1

1

2

High-throughput

0.501

High

608696

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.493

High

704340

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

758785

YEY6
MYG1 protein YER156C

1

0

High-throughput

0.493

High

758820

PBP4
Protein PBP4

1

0

High-throughput

0.493

High

744806

FAT2
Oxalate--CoA ligase

1

0

High-throughput

0.480

High

746222

SHE1
Mitotic spindle-associated protein SHE1

1

0

Small-scale

0.480

High

757413

SPT8
Transcription factor SPT8

1

0

High-throughput

0.480

High

758781

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.480

High

758788

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.480

High

758794

CENPT
Inner kinetochore subunit CNN1

1

0

Small-scale

0.480

High

758813

FIN1
Filament protein FIN1

1

0

Small-scale

0.480

High

698544

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.460

High

747645

HSL7
Protein arginine N-methyltransferase HSL7

1

0

High-throughput

0.460

High

758797

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.460

High

758804

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.460

High

758806

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.460

High

748271

CENPU
Inner kinetochore subunit AME1

1

0

Small-scale

0.458

High

758800

DUO1
DASH complex subunit DUO1

1

0

Small-scale

0.458

High

758821

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

630864

NLE1
Ribosome assembly protein 4

1

12

High-throughput

0.457

High

758792

YJV8
Putative acetyltransferase YJL218W

1

1

High-throughput

0.457

High

758810

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

2

High-throughput

0.457

High

758816

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

1

High-throughput

0.457

High

758826

MPD1
Protein disulfide-isomerase MPD1

1

4

High-throughput

0.457

High

758809

UBC7
Ubiquitin-conjugating enzyme E2 7

1

4

High-throughput

0.457

High

491226

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

511317

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

692785

SPT16
FACT complex subunit SPT16

1

5

High-throughput

0.437

High

758819

CND1
Condensin complex subunit 1

1

1

Small-scale

0.437

High

758814

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

697790

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

698236

CACP
Carnitine O-acetyltransferase, mitochondrial

1

0

High-throughput

0.261

Low

698261

CDC13
Cell division control protein 13

1

0

Small-scale

0.261

Low

745532

MRX3
MIOREX complex component 3

1

0

High-throughput

0.261

Low

750117

YM8C
Uncharacterized deoxyribonuclease YMR262W

1

0

High-throughput

0.261

Low

758799

YD183
Uncharacterized protein YDL183C

1

0

High-throughput

0.261

Low

758803

YG3W
Uncharacterized protein YGR168C

1

0

High-throughput

0.261

Low

758827

LPX1
Peroxisomal membrane protein LPX1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024