Protein: CUL8
Cullin-8 (Cullin-C) (Regulator of Ty1 transposition protein 101)

Gene: CUL8, RTT101
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P47050

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006275 - regulation of DNA replication
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

811013

RBX1
RING-box protein HRT1

4

20

Small-scale

0.703

High

811009

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

5

0

Small-scale

0.692

High

756203

RT107
Regulator of Ty1 transposition protein 107

4

1

Small-scale

0.687

High

811010

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

5

0

Small-scale

0.682

High

539478

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

3

20

Small-scale

0.664

High

692830

SPT16
FACT complex subunit SPT16

2

6

Small-scale

0.624

High

811012

CRT10
Protein CRT10

3

0

Small-scale

0.622

High

356567

H4
Histone H4

2

7

Small-scale

0.612

High

811003

H3
Histone H3

2

7

Small-scale

0.612

High

554685

HSP26
Heat shock protein 26

2

1

High-throughput

0.588

High

675480

PSB7
Proteasome subunit beta type-7

1

10

Small-scale

0.541

High

676171

XPO1
Exportin-1

1

10

High-throughput

0.536

High

811004

CTF4
DNA polymerase alpha-binding protein

1

20

Small-scale

0.536

High

811002

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.525

High

811011

ESC2
Protein ESC2

1

0

Small-scale

0.525

High

392490

H2A2
Histone H2A.2

1

15

High-throughput

0.515

High

811015

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

1

High-throughput

0.515

High

710600

YEL1
Guanine-nucleotide exchange factor YEL1

1

0

High-throughput

0.493

High

759390

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

407155

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

407994

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.479

High

410229

UBC2
Ubiquitin-conjugating enzyme E2 2

1

17

Small-scale

0.479

High

482334

RS18A
Small ribosomal subunit protein uS13A

1

6

High-throughput

0.479

High

544003

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.479

High

549820

UBC4
Ubiquitin-conjugating enzyme E2 4

1

17

Small-scale

0.479

High

631960

RS2
Small ribosomal subunit protein uS5

1

7

High-throughput

0.479

High

662635

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

745744

NU170
Nucleoporin NUP170

1

4

High-throughput

0.479

High

752538

RS20
Small ribosomal subunit protein uS10

1

7

High-throughput

0.479

High

811000

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

811005

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

811006

SLD5
DNA replication complex GINS protein SLD5

1

1

High-throughput

0.479

High

811007

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

811008

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

811016

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

811017

SMC6
Structural maintenance of chromosomes protein 6

1

13

High-throughput

0.479

High

700967

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

811018

LAG2
Cullin-associated NEDD8-dissociated protein 1 homolog

1

1

Small-scale

0.457

High

450092

HSP73
Heat shock protein SSA3

1

18

High-throughput

0.445

High

478318

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

491680

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.445

High

511841

SSB1
Ribosome-associated molecular chaperone SSB1

1

19

High-throughput

0.445

High

766082

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.445

High

768806

SSB2
Ribosome-associated molecular chaperone SSB2

1

19

High-throughput

0.445

High

405702

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

426030

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

472273

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.437

High

480187

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.437

High

645530

RS7A
Small ribosomal subunit protein eS7A

1

5

High-throughput

0.437

High

700498

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

811014

RS10A
Small ribosomal subunit protein eS10A

1

5

High-throughput

0.437

High

810043

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

811001

SOL1
6-phosphogluconolactonase-like protein 1

1

0

High-throughput

0.426

High

588135

HSP60
Heat shock protein 60, mitochondrial

1

11

High-throughput

0.407

High

400195

PLMT
Phosphatidyl-N-methylethanolamine N-methyltransferase

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024