Protein: COT1
Vacuolar zinc transporter COT1 (Cobalt toxicity protein 1)

Gene: COT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 32
UniProt ID: P32798

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0000329 - fungal-type vacuole membrane
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005739 - mitochondrion
GO:0006824 - cobalt ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

745206

COT1
Vacuolar zinc transporter COT1

2

16

High-throughput

0.785

High

628254

ZRC1
Vacuolar zinc transporter ZRC1

1

18

High-throughput

0.590

High

745207

FTH1
Iron transporter FTH1

2

0

High-throughput

0.582

High

745209

ATC2
Calcium-transporting ATPase 2

1

3

High-throughput

0.541

High

745211

VAC8
Vacuolar protein 8

1

4

High-throughput

0.541

High

745222

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

1

High-throughput

0.541

High

745213

EMP47
Protein EMP47

1

0

High-throughput

0.518

High

745215

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.518

High

745219

RAGCD
GTP-binding protein GTR2

1

0

High-throughput

0.518

High

745220

MEH1
Protein MEH1

1

0

High-throughput

0.518

High

745224

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.518

High

737210

HXT1
Low-affinity glucose transporter HXT1

1

3

High-throughput

0.494

High

510328

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

693174

PHO91
Low-affinity phosphate transporter PHO91

1

2

High-throughput

0.479

High

740041

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

4

High-throughput

0.479

High

745210

VTC5
Vacuole transporter chaperone complex subunit 5

1

1

High-throughput

0.479

High

745214

VTC2
Vacuolar transporter chaperone complex subunit 2

1

9

High-throughput

0.479

High

745216

VTC4
Vacuolar transporter chaperone complex subunit 4

1

9

High-throughput

0.479

High

745217

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

745221

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

9

High-throughput

0.479

High

745226

NYV1
Vacuolar v-SNARE NYV1

1

7

High-throughput

0.479

High

547038

PPB
Repressible alkaline phosphatase

1

0

High-throughput

0.458

High

745218

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

523433

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

743665

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.438

High

745223

FMP42
Protein FMP42

1

0

High-throughput

0.438

High

740838

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.437

High

745225

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.437

High

439294

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.407

High

745212

IMB4
Importin subunit beta-4

1

8

High-throughput

0.407

High

745208

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025