Protein: VATD
V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D)

Gene: VATD, VMA8
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P32610

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

603437

VATA
V-type proton ATPase catalytic subunit A

7

10

Small-scale

0.960

High

743685

VATF
V-type proton ATPase subunit F

5

4

Small-scale

0.925

High

592119

VATB
V-type proton ATPase subunit B

4

4

Small-scale

0.892

High

735699

VA0D
V-type proton ATPase subunit d

2

1

High-throughput

0.793

High

645808

VATE
V-type proton ATPase subunit E

7

4

Small-scale

0.740

High

743703

VATG
V-type proton ATPase subunit G

7

3

Small-scale

0.738

High

726554

VATC
V-type proton ATPase subunit C

5

3

Small-scale

0.713

High

743693

VATH
V-type proton ATPase subunit H

5

2

Small-scale

0.711

High

740040

VPP1
V-type proton ATPase subunit a, vacuolar isoform

4

5

Small-scale

0.700

High

743700

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

2

0

Small-scale

0.610

High

743682

ATC2
Calcium-transporting ATPase 2

2

1

High-throughput

0.608

High

743712

RAGAB
GTP-binding protein GTR1

2

2

High-throughput

0.608

High

743705

SKP1
Suppressor of kinetochore protein 1

2

1

Small-scale

0.588

High

743718

RAV2
Regulator of V-ATPase in vacuolar membrane protein 2

2

0

Small-scale

0.585

High

743667

SNC2
Synaptobrevin homolog 2

1

1

High-throughput

0.541

High

743679

FTH1
Iron transporter FTH1

1

0

High-throughput

0.518

High

743714

MEH1
Protein MEH1

1

0

High-throughput

0.518

High

743723

SNA4
Protein SNA4

1

0

High-throughput

0.518

High

743674

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

5

Small-scale

0.515

High

743675

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

1

High-throughput

0.494

High

743698

SNX4
Sorting nexin-4

1

1

Small-scale

0.494

High

743710

PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

1

High-throughput

0.494

High

555239

RAD50
DNA repair protein RAD50

1

1

High-throughput

0.489

High

575322

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.489

High

738619

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.489

High

743669

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.489

High

743706

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.486

High

623808

MYO2
Myosin-2

1

1

Small-scale

0.481

High

575723

BPT1
Bile pigment transporter 1

1

2

High-throughput

0.479

High

693173

PHO91
Low-affinity phosphate transporter PHO91

1

1

High-throughput

0.479

High

736177

YBT1
ATP-dependent bile acid permease

1

2

High-throughput

0.479

High

743666

VATL2
V-type proton ATPase subunit c'

1

1

High-throughput

0.479

High

743684

YCFI
Metal resistance protein YCF1

1

2

High-throughput

0.479

High

743687

VTC1
Vacuolar transporter chaperone complex subunit 1

1

3

High-throughput

0.479

High

743690

SYG1
Protein SYG1

1

1

High-throughput

0.479

High

743695

VTC2
Vacuolar transporter chaperone complex subunit 2

1

5

High-throughput

0.479

High

743699

VTC4
Vacuolar transporter chaperone complex subunit 4

1

5

High-throughput

0.479

High

743715

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

5

High-throughput

0.479

High

743731

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.479

High

743734

YPK9
Vacuolar cation-transporting ATPase YPK9

1

1

High-throughput

0.479

High

547037

PPB
Repressible alkaline phosphatase

1

0

High-throughput

0.458

High

673286

ADP1
Probable ATP-dependent permease

1

0

High-throughput

0.458

High

743677

PFF1
Vacuolar membrane protease

1

0

High-throughput

0.458

High

743683

VTC5
Vacuole transporter chaperone complex subunit 5

1

0

High-throughput

0.458

High

743686

KC13
Casein kinase I homolog 3

1

0

High-throughput

0.458

High

743694

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

0

High-throughput

0.458

High

743707

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.458

High

743721

VBA4
Vacuolar basic amino acid transporter 4

1

0

High-throughput

0.458

High

743725

SMF3
Iron transporter SMF3

1

0

High-throughput

0.458

High

743726

RTC5
Restriction of telomere capping protein 5

1

0

High-throughput

0.458

High

743728

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

0

High-throughput

0.458

High

743732

YVC1
Calcium channel YVC1

1

0

High-throughput

0.458

High

743708

RAGCD
GTP-binding protein GTR2

1

2

High-throughput

0.457

High

743736

VPS5
Vacuolar protein sorting-associated protein 5

1

1

High-throughput

0.457

High

743665

COT1
Vacuolar zinc transporter COT1

1

0

High-throughput

0.438

High

392445

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.437

High

579070

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

679506

CDC48
Cell division control protein 48

1

1

High-throughput

0.437

High

706560

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

708700

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

523407

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

550756

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.282

High

571812

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

728697

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.282

High

743673

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.282

High

743678

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

High-throughput

0.282

High

743692

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.282

High

470115

SPS1
Sporulation-specific protein 1

1

0

High-throughput

0.279

Low

743676

IMB2
Importin subunit beta-2

1

0

High-throughput

0.279

Low

743681

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.279

Low

743717

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.279

Low

743720

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

743730

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.279

Low

743697

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.269

Low

743722

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

666654

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.265

Low

743733

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.265

Low

517956

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

506440

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

410015

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433531

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

434945

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

441798

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

504117

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

647061

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

670496

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

726869

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

743668

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

743670

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

743671

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

743672

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

743680

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

743691

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

743696

RMD8
Sporulation protein RMD8

1

0

High-throughput

0.249

Low

743702

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

743711

H3
Histone H3

1

0

High-throughput

0.249

Low

743713

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

743716

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.249

Low

743719

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

743724

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

743727

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

743729

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

743735

YI002
Uncharacterized protein YIL002W-A

1

0

High-throughput

0.249

Low

672386

STE50
Protein STE50

1

0

High-throughput

0.238

Low

743701

YJ66
Uncharacterized oxidoreductase YJR096W

1

0

High-throughput

0.238

Low

743709

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.238

Low

743688

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

High-throughput

0.232

Low

743689

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low

743704

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025