HitPredict

Interactor 1: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Interactor 2: IRF3 (P70671)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 37099423, 19426678, 24696485, 19805092, 19890330
Identification Methods affinity chromatography technology, comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF, IRF-3~IRF-3
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
and 26 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 419
Mm

1 419
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Service provided by Combinatics, Japan

Last updated: 11Aug2025