HitPredict

Interactor 1: ADAM8 (P78325)
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM 8) (EC 3.4.24.-) (Cell surface antigen MS2) (CD antigen CD156a)
Gene: ADAM8

Interactor 2: FBP1L (Q5T0N5)
Formin-binding protein 1-like (Transducer of Cdc42-dependent actin assembly protein 1) (Toca-1)
Gene: FNBP1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25825872
Identification Methods	phage display, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 605
+	Hs
		1005386 ADAM8_HUMAN (1-824): 0: 643: 100.00		FNBP1_HUMAN (1-605): 3.07e-98: 314: 53.47
+	Hs
		1005380 ADAM8_HUMAN (1-824): 0: 643: 100.00		CIP4_HUMAN (1-599): 2.62e-90: 292: 50.41
+	Hs
		1211650 ADA19_HUMAN (6-824): 1.82e-148: 462: 31.80		FBP1L_HUMAN (1-605): 1.93e-120: 371: 100.00
+	Hs
		1105792 ADAM9_HUMAN (23-733): 5.07e-160: 488: 30.72		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Hs
		209915 ADA12_HUMAN (23-824): 7.03e-155: 477: 34.59		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Hs
		1105835 ADA15_HUMAN (14-796): 9.37e-130: 410: 29.96		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Mm
		1222257 ADAM9_MOUSE (7-774): 1e-160: 490: 31.37		PACN3_MOUSE (188-595): 1.69e-18: 90.3: 11.49
+	Hs
		1461208 ADA18_HUMAN (25-641): 1.04e-113: 364: 26.30		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Mm
		313065 ADA15_MOUSE (37-796): 1.06e-119: 384: 29.41		PACN3_MOUSE (188-595): 1.69e-18: 90.3: 11.49
+	Hs
		161106 ADA10_HUMAN (63-508): 1.88e-23: 108: 24.91		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Hs
		1008460 ADA17_HUMAN (106-530): 1.2e-20: 99.8: 25.45		PACN3_HUMAN (4-311): 2.22e-63: 216: 14.38
+	Hs
		161107 ADA10_HUMAN (63-508): 1.88e-23: 108: 24.91		PACN2_HUMAN (245-595): 4.72e-19: 92.6: 11.60
+	Hs
		161079 ADA10_HUMAN (63-508): 1.88e-23: 108: 24.91		PACN1_HUMAN (187-595): 3.79e-17: 86: 11.62
+	Hs
		1008462 ADA17_HUMAN (106-530): 1.2e-20: 99.8: 25.45		PACN2_HUMAN (245-595): 4.72e-19: 92.6: 11.60
+	Hs
		160954 ADA10_HUMAN (63-508): 1.88e-23: 108: 24.91		GAS7_HUMAN (11-283): 6.17e-15: 79.6: 18.61
+	Hs
		160949 ADA10_HUMAN (63-508): 1.88e-23: 108: 24.91		PPIP1_HUMAN (204-597): 1.02e-14: 78.3: 11.69
+	Hs
		1008450 ADA17_HUMAN (106-530): 1.2e-20: 99.8: 25.45		PACN1_HUMAN (187-595): 3.79e-17: 86: 11.62