HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	12952982
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 909 Hs			1 424
+	Mm
		1222257 ADAM9_MOUSE (5-821): 6.22e-174: 527: 36.10		PACN3_MOUSE (1-424): 9.57e-96: 295: 94.34
+	Hs
		1105792 ADAM9_HUMAN (36-774): 1.09e-174: 529: 37.37		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		209891 ADA12_HUMAN (1-909): 0: 658: 100.00		ITSN1_HUMAN (346-421): 2.69e-15: 80.6: 28.95
+	Hs
		1105835 ADA15_HUMAN (36-880): 5.65e-133: 421: 34.32		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Mm
		313065 ADA15_MOUSE (44-880): 9.4e-130: 413: 33.02		PACN3_MOUSE (1-424): 9.57e-96: 295: 94.34
+	Hs
		1461208 ADA18_HUMAN (38-694): 3.1e-121: 386: 27.67		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		1005380 ADAM8_HUMAN (31-855): 3.17e-147: 457: 33.69		CIP4_HUMAN (16-366): 1.88e-38: 148: 15.34
+	Hs
		1211650 ADA19_HUMAN (5-901): 1.23e-165: 509: 41.72		FBP1L_HUMAN (210-421): 2.15e-12: 70.9: 14.35
+	Hs
		326867 ADA19_HUMAN (5-901): 1.23e-165: 509: 41.72		RIMB1_HUMAN (277-423): 2.84e-10: 64.8: 18.35
+	Hs
		1005382 ADAM8_HUMAN (31-855): 3.17e-147: 457: 33.69		FBP1L_HUMAN (210-421): 2.15e-12: 70.9: 14.35
+	Hs
		1005386 ADAM8_HUMAN (31-855): 3.17e-147: 457: 33.69		FNBP1_HUMAN (225-421): 4.98e-10: 63.6: 15.71
+	Hs
		1105803 ADA15_HUMAN (36-880): 5.65e-133: 421: 34.32		ITSN1_HUMAN (346-421): 2.69e-15: 80.6: 28.95
+	Hs
		1008460 ADA17_HUMAN (196-526): 2.91e-19: 95.5: 27.04		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		161106 ADA10_HUMAN (341-548): 1.12e-18: 93.2: 32.77		PACN3_HUMAN (1-424): 2.79e-93: 289: 100.00
+	Hs
		1008450 ADA17_HUMAN (196-526): 2.91e-19: 95.5: 27.04		PACN1_HUMAN (4-422): 1.2e-86: 272: 48.86
+	Hs
		161079 ADA10_HUMAN (341-548): 1.12e-18: 93.2: 32.77		PACN1_HUMAN (4-422): 1.2e-86: 272: 48.86
+	Hs
		1008462 ADA17_HUMAN (196-526): 2.91e-19: 95.5: 27.04		PACN2_HUMAN (4-422): 1.77e-78: 252: 48.96
+	Hs
		160949 ADA10_HUMAN (341-548): 1.12e-18: 93.2: 32.77		PPIP1_HUMAN (7-422): 1.34e-65: 217: 21.48
+	Hs
		161026 ADA10_HUMAN (341-548): 1.12e-18: 93.2: 32.77		MYO1E_HUMAN (35-422): 2.55e-39: 152: 14.42
+	Hs
		160954 ADA10_HUMAN (341-548): 1.12e-18: 93.2: 32.77		GAS7_HUMAN (363-422): 2.22e-09: 61.3: 34.43