HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.80	0.805

Property	Details
Experiments	26496610, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 427
+	Hs
		1363081 TCPH_HUMAN (4-532): 0: 591: 34.08		DDB2_HUMAN (1-427): 3.18e-95: 294: 100.00
+	Hs
		1407576 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR76_HUMAN (114-412): 2.62e-81: 264: 23.89
+	Hs
		1291941 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		1007186 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (8-311): 5.97e-65: 222: 11.94
+	Hs
		1007118 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (142-427): 3.12e-68: 221: 14.53
+	Hs
		1098369 TCPH_HUMAN (4-532): 0: 591: 34.08		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		1006998 TCPB_HUMAN (1-535): 0: 586: 100.00		ERCC8_HUMAN (114-324): 1.49e-59: 201: 23.21
+	Hs
		1007162 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (14-236): 1.05e-50: 179: 12.56
+	Hs
		965190 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		964840 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (236-427): 6.67e-50: 173: 21.76
+	Hs
		1334162 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (4-184): 1.89e-34: 134: 9.29
+	Hs
		1007146 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (4-184): 1.89e-34: 134: 9.29
+	Hs
		1407594 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (279-427): 9.16e-31: 125: 16.77
+	Hs
		1007196 TCPB_HUMAN (1-535): 0: 586: 100.00		SNR40_HUMAN (273-427): 3.07e-25: 107: 13.21
+	Hs
		1407533 TCPH_HUMAN (4-532): 0: 591: 34.08		TBL1Y_HUMAN (277-427): 7.9e-19: 90.5: 11.88
+	Hs
		984251 TCPH_HUMAN (4-532): 0: 591: 34.08		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57
+	Hs
		1007231 TCPB_HUMAN (1-535): 0: 586: 100.00		TBL1Y_HUMAN (277-427): 7.9e-19: 90.5: 11.88
+	Hs
		984070 TCPB_HUMAN (1-535): 0: 586: 100.00		GBB2_HUMAN (217-427): 6.3e-19: 89.3: 15.57
+	Hs
		209325 TCPH_HUMAN (4-532): 0: 591: 34.08		PRP4_HUMAN (273-421): 1.55e-16: 83.6: 12.67
+	Hs
		209247 TCPB_HUMAN (1-535): 0: 586: 100.00		PRP4_HUMAN (273-421): 1.55e-16: 83.6: 12.67