HitPredict

Interactor 1: NUF2 (Q10173)
Kinetochore protein nuf2 (NMS complex subunit nuf2)
Gene: NUF2

Interactor 2: NDC80 (Q10198)
Kinetochore protein ndc80 (NMS complex subunit ndc80)
Gene: NDC80

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 15728720, 16079914, 28502666
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ndc80_HEC~Nuf2
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
and 7 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 441
Sp

1 624
+ Hs
+ Gg
+ Xl
+ Hs
+ Sc
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024