Interactor 1: ULA1 (Q12059)
NEDD8-activating enzyme E1 regulatory subunit (E1 N-terminus-related protein 2) (Ubiquitin-activating enzyme E1-like 1) (Ubiquitin-like activation protein 1)
Gene: ULA1

Interactor 2: UBA3 (Q99344)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme)
Gene: UBA3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 11805826, 11283351, 10688190, 16429126, 9545234, 18719252, 20826334
Identification Methods tandem affinity purification, two hybrid pooling approach, two hybrid, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0019781 - NEDD8 activating enzyme activity
GO:0045116 - protein neddylation
GO:0120123 - ubiquitin activating enzyme complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 462
Sc

1 299
+ Hs
+ Dm
+ Ce
+ Hs
+ Dm
+ Dm
+ Sc
+ Oc
+ Hs
+ Sc
+ Sp

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Last updated: 15 Jul 2024