Protein: GEA2
ARF guanine-nucleotide exchange factor 2

Gene: GEA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P39993

Gene Ontology (top 5):
GO:0000137 - Golgi cis cisterna
GO:0000139 - Golgi membrane
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

536127

ARF1
ADP-ribosylation factor 1

5

12

Small-scale

0.900

High

793648

ARL1
ADP-ribosylation factor-like protein 1

1

18

Small-scale

0.740

High

816587

GEA2
ARF guanine-nucleotide exchange factor 2

1

9

Small-scale

0.575

High

816589

LCB2
Serine palmitoyltransferase 2

2

1

High-throughput

0.567

High

812277

ATC3
Phospholipid-transporting ATPase DRS2

2

2

Small-scale

0.566

High

802552

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

376306

YPT1
GTP-binding protein YPT1

1

8

Small-scale

0.501

High

732150

COPG
Coatomer subunit gamma

1

5

Small-scale

0.501

High

661634

MPCP
Mitochondrial phosphate carrier protein

1

1

High-throughput

0.489

High

816593

PHB2
Prohibitin-2

1

2

High-throughput

0.489

High

808249

VPS41
Vacuolar protein sorting-associated protein 41

1

1

Small-scale

0.481

High

816596

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

Small-scale

0.480

High

816599

TRS31
Trafficking protein particle complex subunit 31

1

0

Small-scale

0.480

High

816601

TR130
Trafficking protein particle complex II-specific subunit 130

1

0

Small-scale

0.480

High

816609

TRS33
Trafficking protein particle complex subunit 33

1

0

Small-scale

0.480

High

727054

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

781828

GMH1
Protein GMH1

1

1

Small-scale

0.479

High

816598

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

816602

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

816605

IMB1
Importin subunit beta-1

1

3

High-throughput

0.479

High

816606

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

746704

TRS65
Trafficking protein particle complex II-specific subunit 65

1

0

Small-scale

0.460

High

816604

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

Small-scale

0.460

High

779479

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.458

High

816590

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

816591

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

816592

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

544988

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

804188

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

811521

PIK1
Phosphatidylinositol 4-kinase PIK1

1

3

Small-scale

0.439

High

707186

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

816588

IMB4
Importin subunit beta-4

1

2

High-throughput

0.437

High

816595

CDH1
APC/C activator protein CDH1

1

2

Small-scale

0.437

High

816608

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.437

High

613857

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.426

High

628262

ZRC1
Vacuolar zinc transporter ZRC1

1

5

High-throughput

0.407

High

703818

LAC1
Ceramide synthase LAC1

1

2

High-throughput

0.407

High

782210

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

1

High-throughput

0.407

High

802482

LAG1
Ceramide synthase LAG1

1

2

High-throughput

0.407

High

816600

SCS7
Ceramide very long chain fatty acid hydroxylase SCS7

1

2

High-throughput

0.407

High

797840

FTH1
Iron transporter FTH1

2

0

High-throughput

0.307

High

779411

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

811687

CAT8
Regulatory protein CAT8

1

0

High-throughput

0.249

Low

816597

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.249

Low

816603

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

816607

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low

554349

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.232

Low

636313

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.232

Low

796944

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.232

Low

816594

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025