HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: RHG30 (Q7Z6I6)
Rho GTPase-activating protein 30 (Rho-type GTPase-activating protein 30)
Gene: ARHGAP30

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33513601
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1101
+	Hs
		67650 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		RHG32_HUMAN (3-841): 2.61e-117: 402: 28.38
+	Hs
		67654 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		RHG32_HUMAN (3-841): 2.61e-117: 402: 28.38
+	Mm
		988897 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		RHG32_MOUSE (3-892): 2.68e-98: 345: 27.61
+	Hs
		324254 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		FA13A_HUMAN (7-805): 8.43e-92: 318: 15.39
+	Hs
		156404 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		RHG33_HUMAN (3-521): 1.87e-86: 307: 36.99
+	Hs
		212765 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		SRGP3_HUMAN (2-547): 1.02e-75: 273: 16.22
+	Hs
		269537 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		SRGP2_HUMAN (1-609): 1.1e-75: 273: 15.74
+	Hs
		1015505 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		RHG21_HUMAN (4-727): 1.83e-67: 251: 16.88
+	Mm
		988887 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		ABR_MOUSE (3-210): 1.78e-67: 246: 34.58
+	Hs
		1015401 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		RHG05_HUMAN (18-239): 9.02e-65: 242: 25.11
+	Hs
		1015831 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		RHG35_HUMAN (10-241): 5.59e-64: 240: 24.89
+	Hs
		260707 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		OPHN1_HUMAN (4-379): 3.89e-65: 238: 21.11
+	Hs
		586979 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		CHIN_HUMAN (5-212): 4.13e-68: 238: 31.10
+	Hs
		65907 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		RHG42_HUMAN (36-392): 8.85e-65: 238: 24.35
+	Mm
		988896 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		CHIO_MOUSE (5-215): 6.63e-69: 236: 29.25
+	Hs
		914009 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		CHIO_HUMAN (5-215): 2.25e-66: 233: 28.77
+	Hs
		988277 RAC1_HUMAN (1-191): 1e-80: 239: 71.88		RHG04_HUMAN (2-483): 1.39e-62: 233: 18.97
+	Mm
		988900 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		RHG22_MOUSE (11-551): 3.45e-64: 233: 17.77
+	Hs
		1015389 RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00		RHG01_HUMAN (1-222): 4.02e-63: 223: 27.47
+	Mm
		988885 RAC1_MOUSE (1-191): 1e-80: 239: 71.88		RHG01_MOUSE (18-215): 2.16e-18: 91.3: 31.86