HitPredict

Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: MOB3B (Q86TA1)
MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B) (MOB kinase activator-like 2B)
Gene: MOB3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 491 Hs			1 216
+	Hs
		1027437 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MOB1A_HUMAN (13-214): 7.3e-109: 313: 54.46
+	Hs
		1027391 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45
+	Hs
		1023117 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MOB1A_HUMAN (13-214): 7.3e-109: 313: 54.46
+	Hs
		1023070 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		MOB1B_HUMAN (13-214): 6.38e-108: 310: 55.45
+	Hs
		1027459 STK3_HUMAN (1-491): 1.83e-172: 496: 100.00		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1026924 PAK2_HUMAN (6-302): 2.65e-119: 361: 41.04		MOB3C_HUMAN (1-216): 1.12e-116: 332: 71.76
+	Hs
		1023145 STK4_HUMAN (6-491): 3.63e-151: 441: 75.57		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1198329 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		MOB3B_HUMAN (1-216): 3.2e-122: 346: 100.00
+	Dm
		1178607 Q9VEN3_DROME (22-323): 1.36e-124: 379: 50.49		MOB4_DROME (10-204): 4.25e-67: 207: 22.73
+	Hs
		1350192 STK26_HUMAN (22-392): 4.24e-122: 364: 44.27		S4R3N1_HUMAN (10-204): 2.36e-69: 214: 22.22
+	Hs
		1174260 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		MOB3C_HUMAN (1-216): 1.12e-116: 332: 71.76
+	Hs
		1377585 STK24_HUMAN (16-325): 6.03e-124: 370: 50.32		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		131625 STK25_HUMAN (9-426): 4.69e-123: 368: 40.28		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1350187 STK26_HUMAN (22-392): 4.24e-122: 364: 44.27		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Dm
		56110 A1ZBH7_DROME (14-293): 1.86e-76: 262: 45.99		MOB1_DROME (13-214): 3.2e-106: 306: 54.95
+	Dm
		1178592 Q7KV89_DROME (21-320): 2.82e-70: 244: 42.54		MOB4_DROME (10-204): 4.25e-67: 207: 22.73
+	Mm
		949324 TNIK_MOUSE (6-303): 2.2e-70: 245: 44.03		PHOCN_MOUSE (10-204): 1.28e-66: 206: 21.72
+	Hs
		1233571 MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1356420 TNIK_HUMAN (6-303): 4.21e-70: 244: 44.03		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Dm
		1178598 HIPPO_DROME (433-490): 1.74e-22: 102: 55.17		MOB4_DROME (10-204): 4.25e-67: 207: 22.73