HitPredict

Interactor 1: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28636948, 9670010
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043005 - neuron projection
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1484 Hs			1 558
+	Mm
		659449 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		KCC2B_MOUSE (1-558): 0: 616: 77.23
+	Rn
		550161 NMDE2_RAT (1-1484): 0: 1829: 98.45		KCC2D_RAT (1-558): 0: 604: 77.78
+	Hs
		1028155 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Rn
		506719 NMDE2_RAT (1-1484): 0: 1829: 98.45		KCC2A_RAT (1-555): 0: 551: 66.85
+	Mm
		515226 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		KCC2A_MOUSE (1-555): 0: 551: 66.85
+	Rn
		550160 NMDE1_RAT (9-1484): 0: 1506: 52.59		KCC2D_RAT (1-558): 0: 604: 77.78
+	Rn
		506718 NMDE1_RAT (9-1484): 0: 1506: 52.59		KCC2A_RAT (1-555): 0: 551: 66.85
+	Hs
		984259 NMDZ1_HUMAN (13-940): 0: 668: 23.60		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Mm
		659444 NMDZ1_MOUSE (14-940): 0: 671: 23.52		KCC2B_MOUSE (1-558): 0: 616: 77.23
+	Rn
		514948 GRIA4_RAT (17-852): 0: 658: 20.89		KCC2G_RAT (1-558): 0: 619: 86.56
+	Rn
		506693 GRIA1_RAT (11-901): 0: 693: 19.48		KCC2A_RAT (1-555): 0: 551: 66.85
+	Hs
		786716 GRIA1_HUMAN (16-901): 0: 690: 19.56		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Mm
		515217 NMDZ1_MOUSE (14-940): 0: 671: 23.52		KCC2A_MOUSE (1-555): 0: 551: 66.85
+	Hs
		984288 NMDZ1_HUMAN (13-940): 0: 668: 23.60		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Hs
		816227 GRIA4_HUMAN (17-852): 0: 660: 20.89		KCC2A_HUMAN (1-555): 0: 550: 65.23