HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: PHRF1 (Q9P1Y6)
PHD and RING finger domain-containing protein 1
Gene: PHRF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 1649
+	Hs
		1033025 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		NIPBL_HUMAN (453-1441): 5.05e-55: 214: 14.67
+	Hs
		1132872 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		1368868 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		SCAFB_HUMAN (848-1646): 2.49e-44: 179: 19.58
+	Hs
		1088487 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		CHD3_HUMAN (29-273): 3.05e-42: 172: 23.32
+	Hs
		1032967 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		1032924 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		CHD3_HUMAN (29-273): 3.05e-42: 172: 23.32
+	Mm
		1222935 EWS_MOUSE (1-656): 4.64e-42: 163: 94.06		CHD4_MOUSE (16-273): 1.43e-43: 177: 25.00
+	Hs
		1032963 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		MDC1_HUMAN (231-1391): 4.48e-36: 152: 10.19
+	Mm
		1222926 EWS_MOUSE (1-656): 4.64e-42: 163: 94.06		KDM5D_MOUSE (41-291): 7.4e-39: 161: 18.08
+	Hs
		775086 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		775044 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		CHD3_HUMAN (29-273): 3.05e-42: 172: 23.32
+	Hs
		225290 HTSF1_HUMAN (310-448): 3.37e-28: 122: 20.55		CHD4_HUMAN (16-273): 2.11e-44: 179: 23.72
+	Hs
		1109187 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		PRP4K_HUMAN (988-1220): 6.25e-22: 105: 20.75
+	Hs
		225283 HTSF1_HUMAN (310-448): 3.37e-28: 122: 20.55		CHD3_HUMAN (29-273): 3.05e-42: 172: 23.32
+	Hs
		833724 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		KDM5C_HUMAN (169-249): 3.79e-24: 113: 33.33
+	Hs
		1033338 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		PCLO_HUMAN (788-1644): 1.01e-23: 112: 9.50
+	Hs
		775083 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		MDC1_HUMAN (231-1391): 4.48e-36: 152: 10.19
+	Hs
		384135 CO1A1_HUMAN (2-506): 1.12e-18: 92.9: 14.74		ANK2_HUMAN (669-1593): 2.6e-37: 156: 12.99
+	Hs
		124553 EYA2_HUMAN (27-278): 1.49e-18: 91.3: 20.16		KMT2D_HUMAN (451-1321): 3.88e-13: 77.5: 8.84