HitPredict

Interactor 1: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	26186194, 28514442, 14960569, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PID
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 837 Hs			1 197
+	Hs
		1036690 APBA1_HUMAN (1-837): 0: 635: 100.00		LIN7B_HUMAN (1-196): 1.24e-54: 174: 84.69
+	Mm
		74093 APBA1_MOUSE (1-837): 0: 623: 92.76		LIN7C_MOUSE (1-197): 1.56e-57: 181: 100.00
+	Hs
		167691 APBA1_HUMAN (1-837): 0: 635: 100.00		LIN7A_HUMAN (6-194): 6.41e-51: 165: 80.42
+	Hs
		168674 APBA1_HUMAN (1-837): 0: 635: 100.00		CSKP_HUMAN (13-194): 7.06e-31: 120: 20.53
+	Hs
		1006048 APBA1_HUMAN (1-837): 0: 635: 100.00		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Hs
		1036645 APBA1_HUMAN (1-837): 0: 635: 100.00		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Ce
		196211 LIN10_CAEEL (354-837): 1.24e-80: 281: 49.02		Q9U245_CAEEL (3-195): 5.45e-42: 142: 67.88
+	Dm
		723787 Q5BI79_DROME (453-837): 2.72e-78: 279: 61.92		DLG1_DROME (59-176): 3.25e-14: 72.1: 28.46
+	Mm
		1223587 LRRC7_MOUSE (12-742): 5.36e-62: 230: 13.26		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		1006092 LRRC7_HUMAN (48-742): 9.62e-62: 229: 13.37		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Rn
		723869 LRRC7_RAT (12-742): 3.14e-61: 228: 13.26		DLG4_RAT (14-196): 4.35e-23: 97.9: 22.87
+	Mm
		1223689 DLG2_MOUSE (329-735): 7.57e-37: 151: 10.93		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		1006071 DLG2_HUMAN (329-735): 5.16e-36: 148: 10.93		DLG4_HUMAN (14-196): 4.48e-23: 97.9: 22.87
+	Hs
		1091503 DLG2_HUMAN (329-735): 5.16e-36: 148: 10.93		DLG1_HUMAN (50-178): 6.75e-23: 97.1: 30.60
+	Rn
		1224262 DLG2_RAT (329-735): 4.87e-37: 151: 10.93		DLG1_RAT (94-178): 2.15e-21: 92.9: 37.78
+	Mm
		999796 DLG2_MOUSE (329-735): 7.57e-37: 151: 10.93		DLG3_MOUSE (60-164): 1.13e-20: 91: 32.73
+	Hs
		1152416 DLG2_HUMAN (329-735): 5.16e-36: 148: 10.93		DLG3_HUMAN (74-164): 8.63e-20: 88.3: 35.42
+	Mm
		1190725 Q3UP61_MOUSE (226-758): 8.38e-30: 129: 12.48		DLG4_MOUSE (14-196): 1.66e-23: 99.1: 22.87
+	Hs
		1325738 LNX2_HUMAN (387-824): 1.05e-33: 140: 14.99		LNX1_HUMAN (14-179): 4e-17: 80.6: 22.02
+	Mm
		266749 LNX1_MOUSE (310-820): 3.14e-29: 126: 13.54		LNX1_MOUSE (14-179): 1.77e-17: 81.7: 22.62