HitPredict

Interactor 1: FKBP4 (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Interactor 2: S12A5 (Q9H2X9)
Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (hKCC2) (Neuronal K-Cl cotransporter)
Gene: SLC12A5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043025 - neuronal cell body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 459 Hs			1 1139
+	Hs
		1106068 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		S12A5_HUMAN (1-1139): 0: 1205: 100.00
+	Hs
		1038727 FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		1106152 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		S12A7_HUMAN (1-1139): 0: 1054: 69.83
+	Hs
		1106126 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		731608 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A5_HUMAN (1-1139): 0: 1205: 100.00
+	Hs
		124853 AIP_HUMAN (146-416): 2.83e-50: 175: 20.12		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		731679 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A6_HUMAN (2-1139): 0: 1057: 68.33
+	Hs
		731746 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A7_HUMAN (1-1139): 0: 1054: 69.83
+	Hs
		731704 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A4_HUMAN (4-1139): 0: 1045: 66.93
+	Hs
		933513 FKBP4_HUMAN (1-459): 1.84e-150: 437: 100.00		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		933515 FKBP5_HUMAN (1-456): 3.98e-137: 403: 54.83		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		124759 AIP_HUMAN (146-416): 2.83e-50: 175: 20.12		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		731272 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A1_HUMAN (11-1139): 0: 711: 20.90
+	Hs
		933517 FKBP8_HUMAN (26-337): 1.29e-33: 132: 18.15		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		731124 STIP1_HUMAN (267-444): 1.82e-22: 101: 17.42		S12A3_HUMAN (2-1138): 0: 637: 18.98
+	Hs
		1081572 Q0VDC6_HUMAN (149-248): 5.3e-23: 96.5: 25.00		LAT2_HUMAN (168-688): 2.41e-86: 291: 15.28