HitPredict

Interactor 1: S12A3 (P55017)
Solute carrier family 12 member 3 (Na-Cl cotransporter) (NCC) (Na-Cl symporter) (Thiazide-sensitive sodium-chloride cotransporter)
Gene: SLC12A3

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1021 Hs			1 457
+	Hs
		933513 S12A3_HUMAN (1-1021): 0: 1067: 100.00		FKBP4_HUMAN (1-456): 4.32e-138: 406: 53.93
+	Hs
		124759 S12A3_HUMAN (1-1021): 0: 1067: 100.00		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		1106126 S12A4_HUMAN (44-1019): 0: 787: 23.41		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		1038727 S12A4_HUMAN (44-1019): 0: 787: 23.41		FKBP4_HUMAN (1-456): 4.32e-138: 406: 53.93
+	Hs
		1106152 S12A7_HUMAN (38-1019): 0: 763: 22.63		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		933517 S12A3_HUMAN (1-1021): 0: 1067: 100.00		FKBP8_HUMAN (25-330): 2.67e-27: 114: 19.23
+	Hs
		731124 S12A3_HUMAN (1-1021): 0: 1067: 100.00		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		1106068 S12A5_HUMAN (17-960): 0: 721: 22.79		FKBP5_HUMAN (1-457): 6.1e-146: 426: 100.00
+	Hs
		1038701 S12A5_HUMAN (17-960): 0: 721: 22.79		FKBP4_HUMAN (1-456): 4.32e-138: 406: 53.93
+	Hs
		731272 S12A1_HUMAN (30-1019): 0: 941: 51.41		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		124853 S12A4_HUMAN (44-1019): 0: 787: 23.41		AIP_HUMAN (144-414): 3.07e-49: 172: 16.72
+	Hs
		731679 S12A6_HUMAN (17-1019): 0: 799: 22.23		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		731704 S12A4_HUMAN (44-1019): 0: 787: 23.41		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		731746 S12A7_HUMAN (38-1019): 0: 763: 22.63		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		731608 S12A5_HUMAN (17-960): 0: 721: 22.79		STIP1_HUMAN (265-457): 4.42e-23: 103: 17.62
+	Hs
		1081572 LAT2_HUMAN (106-635): 6.41e-104: 337: 13.22		Q0VDC6_HUMAN (151-247): 3.12e-21: 91.4: 27.72