HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: HS902 (Q14568)
Heat shock protein HSP 90-alpha A2 (Heat shock 90 kDa protein 1 alpha-like 3) (Heat shock protein HSP 90-alpha A2 pseudogene) (Heat shock protein family C member 2)
Gene: HSP90AA2P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 776 Hs			1 343
+	Hs
		431829 CUL1_HUMAN (1-776): 0: 911: 100.00		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		438150 CUL1_HUMAN (1-776): 0: 911: 100.00		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		431832 CUL4A_HUMAN (7-776): 0: 781: 30.41		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		431833 CUL4B_HUMAN (7-776): 0: 773: 29.90		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		438153 CUL4A_HUMAN (7-776): 0: 781: 30.41		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		1043352 CUL4B_HUMAN (7-776): 0: 773: 29.90		HS902_HUMAN (1-343): 1.2e-171: 482: 100.00
+	Hs
		438154 CUL4B_HUMAN (7-776): 0: 773: 29.90		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		1043414 CUL4B_HUMAN (7-776): 0: 773: 29.90		Q6PK50_HUMAN (19-343): 2.94e-168: 474: 83.74
+	Hs
		431831 CUL3_HUMAN (9-776): 0: 748: 30.47		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		1041576 CUL3_HUMAN (9-776): 0: 748: 30.47		HS902_HUMAN (1-343): 1.2e-171: 482: 100.00
+	Hs
		438152 CUL3_HUMAN (9-776): 0: 748: 30.47		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		431830 CUL2_HUMAN (13-776): 0: 720: 35.98		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		1041320 CUL2_HUMAN (13-776): 0: 720: 35.98		HS902_HUMAN (1-343): 1.2e-171: 482: 100.00
+	Hs
		438151 CUL2_HUMAN (13-776): 0: 720: 35.98		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		432131 CUL5_HUMAN (2-776): 0: 622: 28.85		HS90A_HUMAN (1-343): 2.69e-171: 495: 94.48
+	Hs
		1055674 CUL5_HUMAN (2-776): 0: 622: 28.85		HS902_HUMAN (1-343): 1.2e-171: 482: 100.00
+	Hs
		438412 CUL5_HUMAN (2-776): 0: 622: 28.85		HS90B_HUMAN (19-343): 9.17e-164: 476: 83.74
+	Hs
		1041725 CUL3_HUMAN (9-776): 0: 748: 30.47		H90B3_HUMAN (19-343): 3.1e-110: 335: 65.54
+	Sc
		367047 CDC53_YEAST (13-776): 0: 628: 31.36		HSP82_YEAST (16-343): 1.93e-139: 413: 62.61
+	Sc
		544559 CDC53_YEAST (13-776): 0: 628: 31.36		HSC82_YEAST (16-343): 1.9e-138: 410: 61.09