HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: MEX3C (Q5U5Q3)
RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C)
Gene: MEX3C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 659
+	Hs
		1041865 CUL3_HUMAN (1-768): 0: 951: 100.00		MEX3B_HUMAN (226-659): 3.43e-166: 489: 54.31
+	Hs
		1041959 CUL3_HUMAN (1-768): 0: 951: 100.00		MEX3D_HUMAN (226-659): 1.36e-148: 447: 51.78
+	Hs
		1036266 CUL3_HUMAN (1-768): 0: 951: 100.00		BIRC2_HUMAN (586-658): 6.42e-14: 77.2: 23.29
+	Hs
		230137 CUL3_HUMAN (1-768): 0: 951: 100.00		MGRN1_HUMAN (588-657): 5.04e-12: 71: 25.35
+	Hs
		1042168 CUL3_HUMAN (1-768): 0: 951: 100.00		RFFL_HUMAN (583-658): 5.05e-12: 69.9: 23.68