HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 559
+	Hs
		1041570 CUL3_HUMAN (1-768): 0: 951: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020253 CUL3_HUMAN (1-768): 0: 951: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		1042980 CUL4A_HUMAN (10-768): 0: 791: 38.32		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1031317 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516505 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1043351 CUL4B_HUMAN (5-768): 0: 779: 36.77		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1040981 CUL1_HUMAN (18-768): 0: 707: 30.57		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1031318 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516506 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031319 CUL4B_HUMAN (5-768): 0: 779: 36.77		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516507 CUL4B_HUMAN (5-768): 0: 779: 36.77		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031315 CUL1_HUMAN (18-768): 0: 707: 30.57		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516503 CUL1_HUMAN (18-768): 0: 707: 30.57		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031316 CUL2_HUMAN (30-768): 0: 672: 26.17		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516504 CUL2_HUMAN (30-768): 0: 672: 26.17		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031416 CUL5_HUMAN (25-768): 0: 597: 23.77		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516626 CUL5_HUMAN (25-768): 0: 597: 23.77		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64