HitPredict

Interactor 1: BTG2 (Q04211)
Protein BTG2 (BTG family member 2) (NGF-inducible protein TIS21)
Gene: BTG2

Interactor 2: CNOT8 (Q9D8X5)
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CCR4-associated factor 8)
Gene: CNOT8

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.80	0.655

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BTG~CAF1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Mm			1 292
+	Hs
		1008535 BTG2_HUMAN (1-158): 1.08e-88: 257: 93.67		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Mm
		1046003 BTG2_MOUSE (1-158): 1.33e-89: 259: 100.00		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Mm
		974917 BTG1_MOUSE (3-158): 4.03e-77: 228: 60.84		CNOT8_MOUSE (1-292): 0: 516: 100.00
+	Hs
		1008536 BTG2_HUMAN (1-158): 1.08e-88: 257: 93.67		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		1233695 Q6IBC8_HUMAN (3-158): 4.03e-77: 228: 60.84		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Hs
		974908 BTG1_HUMAN (3-158): 4.03e-77: 228: 60.84		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Mm
		974916 BTG1_MOUSE (3-158): 4.03e-77: 228: 60.84		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1233696 Q6IBC8_HUMAN (3-158): 4.03e-77: 228: 60.84		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		974909 BTG1_HUMAN (3-158): 4.03e-77: 228: 60.84		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		897475 TOB1_HUMAN (9-123): 8.5e-57: 182: 42.61		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Hs
		1120431 TOB2_HUMAN (9-123): 7.38e-53: 172: 40.87		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Mm
		267214 BTG4_MOUSE (9-116): 1.77e-47: 155: 40.00		CNOT8_MOUSE (1-292): 0: 516: 100.00
+	Hs
		897476 TOB1_HUMAN (9-123): 8.5e-57: 182: 42.61		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		1123546 BTG3_HUMAN (9-116): 4.62e-44: 147: 43.64		CNOT8_HUMAN (1-292): 0: 514: 99.32
+	Hs
		1120432 TOB2_HUMAN (9-123): 7.38e-53: 172: 40.87		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		267213 BTG4_MOUSE (9-116): 1.77e-47: 155: 40.00		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1123549 BTG3_HUMAN (9-116): 4.62e-44: 147: 43.64		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Dm
		1237356 Q6NQY2_DROME (9-125): 2.18e-51: 173: 39.32		Q9VTS4_DROME (2-277): 3.74e-156: 439: 66.20
+	Dm
		1237357 Q6NQY2_DROME (9-125): 2.18e-51: 173: 39.32		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39
+	Dm
		62843 A4V4L0_DROME (9-125): 1.19e-48: 165: 40.17		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39