HitPredict

Interactor 1: Q6IBC8 (Q6IBC8)
Protein BTG1 (B-cell translocation gene 1 protein)
Gene: BTG1

Interactor 2: CNOT8 (Q9UFF9)
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)
Gene: CNOT8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTG~CAF1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 292
+	Mm
		974917 BTG1_MOUSE (1-171): 7.17e-94: 271: 100.00		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Hs
		974908 BTG1_HUMAN (1-171): 7.17e-94: 271: 100.00		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Mm
		974916 BTG1_MOUSE (1-171): 7.17e-94: 271: 100.00		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1233696 Q6IBC8_HUMAN (1-171): 7.17e-94: 271: 100.00		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		974909 BTG1_HUMAN (1-171): 7.17e-94: 271: 100.00		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		1046004 BTG2_MOUSE (5-170): 5.15e-80: 235: 60.84		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Hs
		1008535 BTG2_HUMAN (5-170): 5.32e-80: 235: 62.05		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Mm
		1046003 BTG2_MOUSE (5-170): 5.15e-80: 235: 60.84		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1008536 BTG2_HUMAN (5-170): 5.32e-80: 235: 62.05		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		897475 TOB1_HUMAN (11-142): 7.6e-59: 188: 40.15		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		1120431 TOB2_HUMAN (11-141): 5.77e-55: 178: 40.15		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Mm
		267214 BTG4_MOUSE (11-152): 1.73e-55: 176: 34.21		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Hs
		897476 TOB1_HUMAN (11-142): 7.6e-59: 188: 40.15		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		1120432 TOB2_HUMAN (11-141): 5.77e-55: 178: 40.15		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		267213 BTG4_MOUSE (11-152): 1.73e-55: 176: 34.21		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1123546 BTG3_HUMAN (11-118): 3.9e-44: 147: 42.73		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		1123549 BTG3_HUMAN (11-118): 3.9e-44: 147: 42.73		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Dm
		1237356 Q6NQY2_DROME (11-127): 3.6e-51: 172: 37.61		Q9VTS4_DROME (2-277): 3.74e-156: 439: 66.55
+	Dm
		1237357 Q6NQY2_DROME (11-127): 3.6e-51: 172: 37.61		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39
+	Dm
		62843 A4V4L0_DROME (11-127): 2.04e-48: 165: 38.46		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39