HitPredict

Interactor 1: BTG3 (Q14201)
Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)
Gene: BTG3

Interactor 2: CNOT8 (Q9UFF9)
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)
Gene: CNOT8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BTG~CAF1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 252 Hs			1 292
+	Hs
		1123549 BTG3_HUMAN (1-252): 6.4e-141: 397: 100.00		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		267214 BTG4_MOUSE (1-250): 5.44e-118: 339: 41.18		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Mm
		267213 BTG4_MOUSE (1-250): 5.44e-118: 339: 41.18		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		897475 TOB1_HUMAN (1-136): 1.53e-66: 211: 33.33		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		1120431 TOB2_HUMAN (1-136): 3.13e-60: 195: 30.44		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		897476 TOB1_HUMAN (1-136): 1.53e-66: 211: 33.33		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		974917 BTG1_MOUSE (1-115): 6.63e-52: 168: 40.17		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Mm
		1046004 BTG2_MOUSE (1-115): 2.2e-51: 166: 41.03		CNOT8_MOUSE (1-292): 0: 516: 99.32
+	Hs
		1233695 Q6IBC8_HUMAN (1-115): 6.63e-52: 168: 40.17		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		974908 BTG1_HUMAN (1-115): 6.63e-52: 168: 40.17		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		1008535 BTG2_HUMAN (1-115): 1.85e-51: 166: 41.03		CNOT8_HUMAN (1-292): 0: 514: 100.00
+	Hs
		1120432 TOB2_HUMAN (1-136): 3.13e-60: 195: 30.44		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		974916 BTG1_MOUSE (1-115): 6.63e-52: 168: 40.17		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1233696 Q6IBC8_HUMAN (1-115): 6.63e-52: 168: 40.17		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Hs
		974909 BTG1_HUMAN (1-115): 6.63e-52: 168: 40.17		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Mm
		1046003 BTG2_MOUSE (1-115): 2.2e-51: 166: 41.03		CNOT7_MOUSE (1-282): 2.94e-175: 486: 76.60
+	Hs
		1008536 BTG2_HUMAN (1-115): 1.85e-51: 166: 41.03		CNOT7_HUMAN (1-282): 1.24e-174: 485: 76.24
+	Dm
		1237356 Q6NQY2_DROME (1-136): 6.36e-57: 191: 34.53		Q9VTS4_DROME (2-277): 3.74e-156: 439: 66.55
+	Dm
		1237357 Q6NQY2_DROME (1-136): 6.36e-57: 191: 34.53		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39
+	Dm
		62843 A4V4L0_DROME (1-136): 2.18e-55: 187: 34.78		X2JCC3_DROME (2-244): 4.54e-145: 413: 69.39