HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: FOXQ1 (Q9C009)
Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1)
Gene: FOXQ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25609649, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 403
+	Hs
		1047861 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXQ1_HUMAN (1-403): 6.85e-79: 250: 100.00
+	Hs
		937722 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXA1_HUMAN (8-389): 1.27e-57: 197: 23.69
+	Hs
		1047962 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXI1_HUMAN (66-304): 1.76e-49: 173: 33.61
+	Hs
		938012 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXA3_HUMAN (7-232): 1.95e-49: 172: 30.97
+	Hs
		1047961 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXC1_HUMAN (47-292): 8.65e-47: 170: 27.38
+	Hs
		1047963 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXL1_HUMAN (81-265): 1.61e-47: 167: 40.43
+	Hs
		1048077 TLE3_HUMAN (1-772): 0: 597: 100.00		FOXB1_HUMAN (109-389): 1.33e-47: 167: 26.48
+	Hs
		937721 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXA1_HUMAN (8-389): 1.27e-57: 197: 23.69
+	Hs
		937620 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXG1_HUMAN (28-403): 3.18e-55: 191: 26.29
+	Rn
		92868 D3ZCM7_RAT (1-772): 0: 542: 77.81		FOXG1_RAT (38-403): 6.96e-54: 187: 24.87
+	Hs
		1047886 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXA2_HUMAN (3-333): 8.86e-50: 175: 27.55
+	Hs
		1047807 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXI1_HUMAN (66-304): 1.76e-49: 173: 33.61
+	Hs
		938010 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXA3_HUMAN (7-232): 1.95e-49: 172: 30.97
+	Mm
		1222115 TLE1_MOUSE (1-772): 5.96e-180: 535: 78.09		FOXG1_MOUSE (38-403): 4.78e-54: 187: 24.60
+	Hs
		1047808 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXL1_HUMAN (81-265): 1.61e-47: 167: 40.43
+	Hs
		1047857 TLE1_HUMAN (1-772): 0: 553: 77.96		FOXB1_HUMAN (109-389): 1.33e-47: 167: 26.48
+	Hs
		1048154 TLE4_HUMAN (1-772): 0: 541: 80.52		FOXI1_HUMAN (66-304): 1.76e-49: 173: 33.61
+	Hs
		1048155 TLE4_HUMAN (1-772): 0: 541: 80.52		FOXL1_HUMAN (81-265): 1.61e-47: 167: 40.43
+	Hs
		1048176 TLE4_HUMAN (1-772): 0: 541: 80.52		FOXB1_HUMAN (109-389): 1.33e-47: 167: 26.48
+	Hs
		938011 TLE2_HUMAN (1-772): 5.37e-150: 458: 62.35		FOXA3_HUMAN (7-232): 1.95e-49: 172: 30.97