HitPredict

Interactor 1: TFDP2 (Q14188)
Transcription factor Dp-2 (E2F dimerization partner 2)
Gene: TFDP2

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	24981860, 28514442, 27705803, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 350
+	Hs
		1050537 TFDP1_HUMAN (3-430): 0: 624: 60.47		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		1050566 TFDP2_HUMAN (1-446): 0: 700: 100.00		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		1050532 TFDP1_HUMAN (3-430): 0: 624: 60.47		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		987969 TFDP1_HUMAN (3-430): 0: 624: 60.47		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Mm
		996146 TFDP1_MOUSE (3-430): 0: 607: 59.82		RING2_MOUSE (85-303): 2.38e-32: 125: 14.49