HitPredict

Interactor 1: NMDZ1 (Q05586)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) (hNR1)
Gene: GRIN1

Interactor 2: NMDZ1 (Q05586)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) (hNR1)
Gene: GRIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15888440
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0001540 - amyloid-beta binding
GO:0004972 - NMDA glutamate receptor activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
and 50 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 938
Hs

1 938
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+ Rn
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+ Xl
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Last updated: 11Aug2025