Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: BAKOR (Q6ZNE5)
Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)
Gene: ATG14

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.772

The method score is based on:

Property Details
Experiments 18843052, 19050071, 28514442, 28757208, 28404643, 29866835, 28431397, 27383850, 28059666, 29313410, 24166503, 22314358, 27621469, 24879154, 26549445, 24141421, 25275521, 19270693, 31696776, 33961781 and 30 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, x-ray crystallography, biochemical, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid prey pooling approach and 2 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0005776 - autophagosome
GO:0005789 - endoplasmic reticulum membrane
and 12 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 450
Hs

1 492
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024