HitPredict

Interactor 1: Q18477 (Q18477)
Histone deacetylase domain-containing protein
Gene: hda-11

Interactor 2: SEM2 (Q8T3B9)
Transcription factor sem-2 (Sex muscle abnormal protein 2)
Gene: sem-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Ce			1 404
+	Rn
		1118086 HDAC1_RAT (13-314): 1.7e-131: 385: 21.59		LEF1_RAT (6-190): 1.52e-42: 155: 22.06
+	Hs
		1038795 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		LEF1_HUMAN (6-190): 1.87e-42: 155: 22.55
+	Hs
		727863 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		SOX6_HUMAN (80-237): 1.86e-38: 149: 37.20
+	Hs
		233836 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		HBP1_HUMAN (25-165): 2.86e-38: 146: 26.90
+	Hs
		1038736 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		HM20A_HUMAN (6-226): 3.51e-34: 131: 17.70
+	Hs
		883315 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		SOX8_HUMAN (7-354): 4.43e-32: 127: 20.96
+	Mm
		140273 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		Q60I23_MOUSE (60-306): 2.59e-32: 125: 27.53
+	Mm
		140241 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		SOX2_MOUSE (60-306): 6.43e-32: 124: 27.53
+	Xl
		1193361 Q7ZYT5_XENLA (12-314): 7.53e-130: 380: 20.57		Q90ZB8_XENLA (6-191): 5.67e-33: 128: 21.51
+	Hs
		818023 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		SOX2_HUMAN (60-306): 9.38e-32: 124: 27.94
+	Hs
		1038645 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		CIC_HUMAN (16-337): 1.69e-29: 123: 16.26
+	Mm
		140321 HDAC1_MOUSE (13-314): 1.61e-131: 385: 21.59		TF7L1_MOUSE (4-318): 8.68e-30: 122: 17.72
+	Hs
		727903 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		SOX6_HUMAN (80-237): 1.86e-38: 149: 37.20
+	Hs
		1038764 HDAC1_HUMAN (13-314): 2.61e-131: 384: 21.59		HM20B_HUMAN (55-167): 1.22e-29: 118: 25.44
+	Hs
		1270459 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		HM20A_HUMAN (6-226): 3.51e-34: 131: 17.70
+	Ce
		1090082 Q18477_CAEEL (1-334): 7.24e-125: 363: 100.00		EGL13_CAEEL (23-222): 4.63e-30: 122: 29.13
+	Hs
		818314 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		SOX2_HUMAN (60-306): 9.38e-32: 124: 27.94
+	Hs
		1270390 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		CIC_HUMAN (16-337): 1.69e-29: 123: 16.26
+	Ce
		184841 HDA1_CAEEL (6-314): 1.4e-121: 359: 21.43		POP1_CAEEL (16-298): 4.29e-30: 122: 16.43
+	Hs
		1270484 HDAC2_HUMAN (10-314): 8.76e-121: 358: 20.76		HM20B_HUMAN (55-167): 1.22e-29: 118: 25.44