HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 543
+	Hs
		411642 LCK_HUMAN (1-509): 0: 661: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		412325 FYN_HUMAN (30-507): 0: 586: 59.01		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		454845 FGR_HUMAN (1-507): 0: 579: 52.76		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		411639 LCK_HUMAN (1-509): 0: 661: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		411588 LCK_HUMAN (1-509): 0: 661: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		846519 BLK_HUMAN (1-509): 0: 557: 59.35		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		412086 FYN_HUMAN (30-507): 0: 586: 59.01		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		433290 YES_HUMAN (26-507): 0: 581: 58.06		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		454809 FGR_HUMAN (1-507): 0: 579: 52.76		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		412084 FYN_HUMAN (30-507): 0: 586: 59.01		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		454808 FGR_HUMAN (1-507): 0: 579: 52.76		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		826575 BLK_HUMAN (1-509): 0: 557: 59.35		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		411996 FYN_HUMAN (30-507): 0: 586: 59.01		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		433248 YES_HUMAN (26-507): 0: 581: 58.06		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		454796 FGR_HUMAN (1-507): 0: 579: 52.76		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821128 BLK_HUMAN (1-509): 0: 557: 59.35		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		411647 LCK_HUMAN (1-509): 0: 661: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		412093 FYN_HUMAN (30-507): 0: 586: 59.01		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		454812 FGR_HUMAN (1-507): 0: 579: 52.76		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843115 BLK_HUMAN (1-509): 0: 557: 59.35		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79