HitPredict

Interactor 1: UB2R2 (Q29503)
Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)
Gene: UBE2R2

Interactor 2: UBA1 (Q29504)
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Ubiquitin-activating enzyme E1)
Gene: UBA1

Species: Oryctolagus cuniculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	2174883
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 238 Oc			1 1058
+	Hs
		607022 UB2R1_HUMAN (1-238): 4.37e-90: 266: 79.41		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607099 UB2R2_HUMAN (1-238): 1.22e-81: 245: 100.00		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607190 UB2D4_HUMAN (8-167): 7.92e-72: 217: 31.68		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607026 UB2D1_HUMAN (8-167): 2.78e-71: 216: 31.68		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607050 UB2D2_HUMAN (8-167): 2.85e-71: 216: 29.19		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607039 UB2D3_HUMAN (8-167): 3.59e-70: 213: 29.81		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607046 UB2G1_HUMAN (13-174): 4.73e-69: 211: 51.85		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Hs
		607038 UB2G2_HUMAN (8-160): 1.03e-65: 202: 49.67		UBA1_HUMAN (1-1058): 0: 1372: 96.69
+	Sp
		293848 UBC4_SCHPO (8-166): 3.36e-70: 213: 30.00		UBA1_SCHPO (42-1053): 0: 1083: 53.69
+	Hs
		48104 UB2D1_HUMAN (8-167): 2.78e-71: 216: 31.68		UBA6_HUMAN (12-1057): 0: 1073: 41.28
+	Hs
		48107 UB2D2_HUMAN (8-167): 2.85e-71: 216: 29.19		UBA6_HUMAN (12-1057): 0: 1073: 41.28
+	Sp
		116506 UBC7_SCHPO (7-172): 2.33e-66: 204: 44.58		UBA1_SCHPO (42-1053): 0: 1083: 53.69
+	Hs
		48106 UB2D3_HUMAN (8-167): 3.59e-70: 213: 29.81		UBA6_HUMAN (12-1057): 0: 1073: 41.28
+	Sc
		539443 UBC3_YEAST (5-235): 3.47e-69: 216: 35.04		UBA1_YEAST (35-1057): 0: 1070: 51.06
+	Sp
		293852 UBC15_SCHPO (7-151): 6.12e-65: 200: 51.03		UBA1_SCHPO (42-1053): 0: 1083: 53.69
+	Sc
		608719 UBC7_YEAST (8-161): 4.1e-68: 208: 45.46		UBA1_YEAST (35-1057): 0: 1070: 51.06
+	Sc
		549788 UBC4_YEAST (8-166): 1.66e-67: 206: 31.88		UBA1_YEAST (35-1057): 0: 1070: 51.06
+	Hs
		48105 UB2G2_HUMAN (8-160): 1.03e-65: 202: 49.67		UBA6_HUMAN (12-1057): 0: 1073: 41.28
+	Sc
		854609 UBC7_YEAST (8-161): 4.1e-68: 208: 45.46		UBA2_YEAST (61-450): 4.41e-80: 276: 15.42
+	Hs
		919796 UB2D2_HUMAN (8-167): 2.85e-71: 216: 29.19		UBA3_HUMAN (833-1018): 5.68e-12: 71.3: 17.95