Interactor 1: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS
Interactor 2: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.740 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16273344 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Y_phosphatase~fn3, Y_phosphatase~Y_phosphatase |
| Common GO terms | GO:0005886 - plasma membrane GO:0043204 - perikaryon |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
