HitPredict

Interactor 1: G5ECD7 (G5ECD7)
cGMP-dependent protein kinase interacting domain-containing protein
Gene: mel-11

Interactor 2: H2L2C8 (H2L2C8)
Alpha-actinin, sarcomeric
Gene: atn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	14704431, 18692475
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1124 Ce			1 823
+	Ce
		110762 G5ECD7_CAEEL (1-1124): 9.38e-150: 479: 100.00		Q23158_CAEEL (1-823): 0: 550: 95.41
+	Ce
		113646 G5EG29_CAEEL (179-1124): 5.73e-64: 237: 36.33		Q9XVU8_CAEEL (1-823): 0: 571: 100.00
+	Hs
		555645 DAPK1_HUMAN (124-555): 1.05e-40: 166: 14.13		ACTN1_HUMAN (1-823): 0: 583: 61.21
+	Hs
		224667 DAPK1_HUMAN (124-555): 1.05e-40: 166: 14.13		ACTN4_HUMAN (1-823): 0: 551: 61.21
+	Hs
		171124 MYPT1_HUMAN (4-218): 1.49e-27: 123: 11.91		ACTN4_HUMAN (1-823): 0: 551: 61.21
+	Mm
		86327 ANK3_MOUSE (2-642): 1.45e-72: 267: 13.73		B9EKJ1_MOUSE (215-791): 6.04e-19: 94.8: 15.11
+	Mm
		109260 ANK3_MOUSE (2-642): 1.45e-72: 267: 13.73		Q3UGX2_MOUSE (181-801): 4.48e-15: 82: 12.72
+	Mm
		109265 ANK3_MOUSE (2-642): 1.45e-72: 267: 13.73		SPTB2_MOUSE (174-740): 2.69e-10: 66.6: 10.18
+	Hs
		1091395 ANK3_HUMAN (7-535): 3.3e-59: 226: 13.33		SPTN1_HUMAN (218-688): 5.95e-20: 97.9: 13.29
+	Hs
		1091457 ANK3_HUMAN (7-535): 3.3e-59: 226: 13.33		SPTN4_HUMAN (183-801): 1.71e-14: 80.4: 10.87
+	Hs
		174752 ANK3_HUMAN (7-535): 3.3e-59: 226: 13.33		SPTN2_HUMAN (184-762): 2.03e-14: 80.1: 13.62
+	Hs
		1028748 ANK3_HUMAN (7-535): 3.3e-59: 226: 13.33		SPTB2_HUMAN (174-740): 9.52e-10: 64.6: 10.35
+	Hs
		920439 DAPK1_HUMAN (124-555): 1.05e-40: 166: 14.13		SPTN1_HUMAN (218-688): 5.95e-20: 97.9: 13.29
+	Hs
		174726 DAPK1_HUMAN (124-555): 1.05e-40: 166: 14.13		SPTN2_HUMAN (184-762): 2.03e-14: 80.1: 13.62
+	Hs
		920429 DAPK1_HUMAN (124-555): 1.05e-40: 166: 14.13		SPTB2_HUMAN (174-740): 9.52e-10: 64.6: 10.35
+	Hs
		540235 ANK1_HUMAN (113-588): 1.32e-35: 149: 10.92		SPTB1_HUMAN (181-801): 3.11e-12: 72.7: 12.56
+	Hs
		592928 ANK1_HUMAN (113-588): 1.32e-35: 149: 10.92		SPTB2_HUMAN (174-740): 9.52e-10: 64.6: 10.35
+	Hs
		1030639 ANK2_HUMAN (74-289): 5.05e-11: 69.7: 30.05		SPTN1_HUMAN (218-688): 5.95e-20: 97.9: 13.29
+	Hs
		174745 ANK2_HUMAN (74-289): 5.05e-11: 69.7: 30.05		SPTN2_HUMAN (184-762): 2.03e-14: 80.1: 13.62
+	Hs
		1028731 ANK2_HUMAN (74-289): 5.05e-11: 69.7: 30.05		SPTB2_HUMAN (174-740): 9.52e-10: 64.6: 10.35