HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: NACC1 (Q96RE7)
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)
Gene: NACC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	37019189, 17699672
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 527
+	Hs
		1113267 CUL3_HUMAN (1-768): 0: 943: 100.00		KLH12_HUMAN (10-268): 7.5e-67: 227: 18.63
+	Hs
		1113454 CUL3_HUMAN (1-768): 0: 943: 100.00		KLH24_HUMAN (3-272): 3.94e-66: 226: 18.48
+	Hs
		329059 CUL3_HUMAN (1-768): 0: 943: 100.00		KLHL2_HUMAN (9-322): 7.24e-63: 217: 15.46
+	Hs
		1113453 CUL3_HUMAN (1-768): 0: 943: 100.00		KLH17_HUMAN (8-275): 7.85e-62: 215: 16.12
+	Hs
		1113681 CUL3_HUMAN (1-768): 0: 943: 100.00		Q8N4I8_HUMAN (9-276): 1.24e-64: 214: 15.75
+	Hs
		334556 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT7A_HUMAN (1-431): 9.2e-62: 214: 16.86
+	Hs
		320822 CUL3_HUMAN (1-768): 0: 943: 100.00		KLH18_HUMAN (1-265): 1.94e-61: 213: 17.58
+	Hs
		1113274 CUL3_HUMAN (1-768): 0: 943: 100.00		KLH26_HUMAN (7-314): 3.75e-60: 210: 16.35
+	Hs
		1113077 CUL3_HUMAN (1-768): 0: 943: 100.00		KEAP1_HUMAN (3-260): 4.48e-58: 205: 14.66
+	Hs
		1113277 CUL3_HUMAN (1-768): 0: 943: 100.00		Q53SE7_HUMAN (21-452): 1.95e-56: 198: 15.08
+	Hs
		832715 CUL3_HUMAN (1-768): 0: 943: 100.00		BCL6_HUMAN (6-350): 3.65e-49: 182: 19.07
+	Hs
		1051368 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT16_HUMAN (4-346): 1.75e-48: 180: 20.52
+	Hs
		1094496 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT17_HUMAN (7-365): 2.93e-45: 172: 20.89
+	Hs
		182019 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT22_HUMAN (4-289): 7.88e-43: 163: 23.64
+	Hs
		166522 CUL3_HUMAN (1-768): 0: 943: 100.00		BACH1_HUMAN (4-263): 1.11e-38: 152: 20.53
+	Hs
		161296 CUL3_HUMAN (1-768): 0: 943: 100.00		ENC1_HUMAN (7-127): 5.16e-39: 151: 28.80
+	Hs
		208839 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT24_HUMAN (12-223): 1.67e-37: 148: 22.48
+	Hs
		229325 CUL3_HUMAN (1-768): 0: 943: 100.00		ZBT14_HUMAN (1-216): 3.82e-38: 147: 24.03
+	Hs
		1113639 CUL3_HUMAN (1-768): 0: 943: 100.00		KBTB2_HUMAN (12-128): 2.49e-11: 68.2: 33.61
+	Hs
		1113553 CUL3_HUMAN (1-768): 0: 943: 100.00		KAISO_HUMAN (12-139): 5.44e-11: 67: 35.39