Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1
Interactor 2: SPTN4 (Q9H254)
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Gene: SPTBN4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17607528 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CH~EF-hand_7, EF-hand_7~Spectrin, CH~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin |
| Common GO terms | GO:0003779 - actin binding GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008091 - spectrin and 8 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
