HitPredict

Interactor 1: Q53FC7 (Q53FC7)
Heat shock 70kDa protein 6 (HSP70B') variant
Gene: Q53FC7

Interactor 2: BAG1 (Q99933)
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)
Gene: BAG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 345
+	Hs
		564166 HSP76_HUMAN (1-643): 0: 990: 99.22		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Mm
		571857 HS71B_MOUSE (5-643): 0: 960: 80.31		BAG1_MOUSE (1-345): 0: 520: 71.27
+	Rn
		69526 HSP7C_RAT (4-615): 0: 958: 78.76		BAG1_RAT (1-345): 0: 518: 69.83
+	Hs
		714058 HS71L_HUMAN (1-643): 0: 981: 78.85		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		504647 HSP7C_HUMAN (4-615): 0: 959: 78.76		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		871754 HSP72_HUMAN (3-643): 0: 945: 77.14		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00