HitPredict

Interactor 1: SEPT6 (Q14141)
Septin-6
Gene: SEPTIN6

Interactor 2: SEPT5 (Q99719)
Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1)
Gene: SEPTIN5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 18330356, 25416956, 24722188, 32814053
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Septin~Septin
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005940 - septin ring
GO:0008021 - synaptic vesicle
GO:0008104 - intracellular protein localization
and 5 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 434
Hs

1 369
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Service provided by Combinatics, Japan

Last updated: 11Aug2025