HitPredict

Interactor 1: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Interactor 2: TRIM5 (Q9C035)
Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5)
Gene: TRIM5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 565 Hs			1 493
+	Hs
		1121201 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		1019313 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		271189 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		1223388 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI22_HUMAN (1-493): 8.67e-130: 387: 50.98
+	Hs
		271032 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		RO52_HUMAN (1-492): 6.35e-136: 402: 39.80
+	Hs
		1318717 UBP21_HUMAN (223-560): 2.89e-97: 308: 18.85		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		1273788 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI11_HUMAN (2-491): 2.14e-121: 365: 31.91
+	Hs
		536961 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI27_HUMAN (1-492): 5.51e-121: 365: 29.21
+	Hs
		271195 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		800627 UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81		TRIM5_HUMAN (1-493): 3.88e-147: 432: 100.00
+	Hs
		271027 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI27_HUMAN (1-492): 5.51e-121: 365: 29.21
+	Hs
		271184 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI34_HUMAN (1-493): 9.36e-114: 346: 55.75
+	Hs
		800631 UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81		TRI39_HUMAN (6-492): 6.9e-127: 381: 27.48
+	Hs
		1273967 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI35_HUMAN (2-491): 7.11e-93: 292: 21.40
+	Hs
		271136 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI50_HUMAN (5-481): 4.35e-98: 306: 24.74
+	Hs
		271221 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI35_HUMAN (2-491): 7.11e-93: 292: 21.40
+	Hs
		800578 UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		800600 UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81		TRIML_HUMAN (2-493): 7.91e-101: 312: 25.10
+	Hs
		1019375 UBP36_HUMAN (225-564): 4.97e-62: 223: 20.69		TRI26_HUMAN (1-490): 4.61e-103: 320: 25.73
+	Hs
		1273857 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI31_HUMAN (1-269): 5.66e-40: 150: 31.25