HitPredict

Interactor 1: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 565 Hs			1 530
+	Hs
		1269294 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1270054 UBP3_HUMAN (105-563): 1.97e-121: 369: 19.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377377 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		370153 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369123 UBP8_HUMAN (177-564): 2.41e-101: 332: 19.80		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		488004 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		1269805 UBP36_HUMAN (225-564): 4.97e-62: 223: 20.69		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		271015 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377159 UBP8_HUMAN (177-564): 2.41e-101: 332: 19.80		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		370605 UBP36_HUMAN (225-564): 4.97e-62: 223: 20.69		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487650 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487848 UBP22_HUMAN (123-560): 1.99e-114: 351: 17.39		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		271023 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Mm
		59436 UBP2_MOUSE (180-560): 4.43e-106: 333: 20.56		A3KN90_MOUSE (141-408): 4.19e-38: 151: 34.51
+	Hs
		487213 UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		259262 UBP12_HUMAN (209-556): 5.21e-90: 283: 18.92		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59